Navegando por Palavras-chave "Retinitis"
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- ItemAcesso aberto (Open Access)Clinical features and outcomes of AIDS-related cytomegalovirus retinitis in the era of highly active antiretroviral therapy(Conselho Brasileiro de Oftalmologia, 2010-02-01) Arantes, Tiago Eugênio Faria E [UNIFESP]; Garcia, Claudio Renato [UNIFESP]; Saraceno, Janaína Jamile Ferreira [UNIFESP]; Muccioli, Cristina [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)PURPOSE: To describe the features and outcomes of patients with AIDS-related cytomegalovirus retinitis after highly active antiretroviral therapy availability. METHODS: Retrospective chart review of 30 consecutive patients (44 eyes) with AIDS and newly diagnosed, active AIDS-related cytomegalovirus retinitis, examined from January 2005 to December 2007. RESULTS: The mean age was 34.8 years, 18 patients (60.0%) were male and median duration of AIDS was 90 months. Nineteen patients (63.3%) had evidence of highly active antiretroviral therapy failure and median CD4+ lymphocyte count was 12.5 cells/µl. Visual acuity at presentation was 20/40 or better in 27 eyes (61.4%). Retinitis involved Zone 1 in 13 eyes (39.5%). Despite specific anti-AIDSrelated cytomegalovirus therapy, 16 eyes (36.4%) presented relapse of retinitis and 10 eyes (22.7%) lost at least three lines of vision. When compared to highly active antiretroviral therapy responsive patients, eyes of highly active antiretroviral therapy failure patients were more likely to develop relapse of retinitis (p=0.03) and loss of at least three lines of vision (p=0.03). CONCLUSION: The patients in this series are essentially young men with longstanding AIDS, non-responsive to highly active antiretroviral therapy and with a similar immunological profile as noted before highly active antiretroviral therapy era. These findings have implications for the management of the disease and confirm the magnitude of rational periodic screening after diagnosis of AIDS.
- ItemSomente MetadadadosDiagnóstico pela laser flare fotometria da inflamação intra-ocular e da retinite por citomegalovírus em pacientes infectados pelo vírus da imunodeficiência humana(Universidade Federal de São Paulo (UNIFESP), 1993) Muccioli, Cristina [UNIFESP]; Belfort, Rubens Junior [UNIFESP]
- ItemAcesso aberto (Open Access)Intraretinal worm documented by optical coherence tomography in a patient with diffuse unilateral subacute neuroretinitis: case report(Conselho Brasileiro de Oftalmologia, 2010-10-01) Cunha, Leonardo Provetti; Costa-cunha, Luciana Virgínia Ferreira; Souza, Eduardo Cunha De [UNIFESP]; Monteiro, Mário Luiz R.; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)Our purpose is to report a case of diffuse unilateral subacute neuroretinitis (DUSN) in which an ophthalmoscopically visible worm was found and optical coherence tomography (OCT) scans allowed the precise localization of the parasite in the intraretinal layers. Our findings suggest that the parasite moves in the inner portions of the retina possibly explaining the severe degenerative neural changes that it causes.
- ItemAcesso aberto (Open Access)Remote hypofluorescent dots in recurrent ocular toxoplasmosis on indocyanine green angiography(Conselho Brasileiro de Oftalmologia, 2007-12-01) Amaro, Miguel Hage [UNIFESP]; Muccioli, Cristina [UNIFESP]; Abreu, Mariza Toledo [UNIFESP]; Belfort, Rubens Junior [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)PURPOSE: To report the findings of indocyanine green angiography performed in patients with recurrent ocular toxoplasmosis. METHODS: Institutional prospective analysis of 23 eyes from 23 immunocompetent patients with recurrent ocular toxoplasmosis aged between 17 and 41 years. These patients underwent a complete ocular examination including indocyanine green angiography. RESULTS: Multiple hypofluorescent spots distant from the recurrent active lesion of retinochoroidal toxoplasmosis were found in 26.08% of the patients. We also found multiple hypofluorescent satellite dots in 69.56% of the patients. CONCLUSION: These remote dots seen suggest either a more widespread choroidal involvement in this disease and this can represent simply remote collections of inflammatory cells or subclinical infection.
- ItemAcesso aberto (Open Access)Retinal nerve fiber layer atrophy as relevant feature for diffuse unilateral subacute neuroretinitis (DUSN): case series(Conselho Brasileiro de Oftalmologia, 2010-04-01) Casella, Antonio Marcelo Barbante; Farah, Michel Eid [UNIFESP]; Souza, Eduardo Cunha de [UNIFESP]; Belfort, Rubens Junior [UNIFESP]; Oguido, Ana Paula Miyagusko Taba; State University of Londrina; Universidade Federal de São Paulo (UNIFESP); UELPURPOSE: To report the findings of optical coherence tomography (OCT) in three cases of diffuse unilateral subacute neuroretinitis (DUSN). METHODS: Three young patients with confirmed diagnosis of diffuse unilateral subacute neuroretinitis were followed-up using Stratus® OCT. RESULTS: Optical coherence tomography findings included retinal nerve fiber layer atrophy and focal edema where the worm was initially lodged. In two patients we could identify the worm by optical coherence tomography as an area of hiper-reflectivity. The worms were laser photocoagulated and post-treatment optical coherence tomography scanning revealed improvement of edema, nerve fiber layer thinning and a retinal hyper-reflectivity where laser had been applied. CONCLUSION: The main finding reported here is the potential of optical coherence tomography in detecting the presence of retinal nerve fiber layer atrophy and focal retinal edema in areas affected by the worm. Optical coherence tomography can be used to distinguish diffuse unilateral subacute neuroretinitis from other mimicking diseases like punctate outer retinitis, when there are no retinal fiber layer atrophy.
- ItemAcesso aberto (Open Access)Retinite idiopática, vasculite, aneurismas e neurorretinite (IRVAN): relato de caso(Conselho Brasileiro de Oftalmologia, 2012-04-01) Rodrigues, Kelly Fernandes de Paula [UNIFESP]; Lima, Verônica Castro [UNIFESP]; Arantes, Tiago Eugênio Faria e [UNIFESP]; Matos, Kimble Teixeira Fonseca [UNIFESP]; Muccioli, Cristina [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)A case of a 14 year-old boy that was admitted complaining of bilateral ocular visual blurring for 2 years is reported. The ophthalmological examination disclosed bilateral mild optic disc hyperemia and swelling, retinal exudation, few retinal hemorrhages, multiple aneurysms, as well as vasculitis. Fluorescein angiography showed extensive peripheral retinal ischemia, dilatations and hyperfluorescence of the vessels walls, and leakage of the optic disc in the late phases in both eyes. This rare case represents an entity characterized by peripheral retinal vascular occlusion, retinal vasculitis, multiple posterior retinal aneurysms, and neuroretinitis (IRVAN). Systemic evaluation and laboratory work-up did not suggest any systemic abnormality. Panretinal laser photocoagulation was performed in both eyes, and the patient was treated with oral prednisone with maintenance of the visual acuity after 1 year of follow-up. Laser treatment should be considered when angiographic evidence of widespread retinal no perfusion is present, and before the development of signs of retinal neovascularization.
- ItemAcesso aberto (Open Access)Seria o Ancylostoma caninum um dos agentes da neurorretinite sub-aguda difusa unilateral (D.U.S.N.) no Brasil?(Conselho Brasileiro de Oftalmologia, 2001-10-01) Casella, Antônio Marcelo Barbante; Machado, Roberto Augusto; Tsuro, Andréa; Hato, Maurício; Costa, Rogerio Alves [UNIFESP]; Farah, Michel Eid [UNIFESP]; Universidade Estadual de Londrina Setor de Oftalmologia; Universidade Federal de São Paulo (UNIFESP)The autors present a confirmed case of diffuse unilateral subacute neuroretinitis (D.U.S.N.) with identification of the worm in a 6-year-old child with symptoms of cutaneous larva migrans, as well as analysis of 7 other cases of D.U.S.N. and association with cutaneous larva migrans or positive sorology for Toxocara canis. This is the first described case in the literature of the association between D.U.S.N. and cutaneous larva migrans in its active form.