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- ItemAcesso aberto (Open Access)Peripheral Vascular Resistance Impairment during Isometric Physical Exercise in Normotensive Offspring of Hypertensive Parents(Arquivos Brasileiros Cardiologia, 2017) Portela, Natalia; Amaral, Josaria Ferraz; de Carvalho Mira, Pedro Augusto; de Souza, Livia Victorino [UNIFESP]; Martinez, Daniel Godoy; Laterza, Mateus CamarotiBackground: A family history of hypertension is associated with vascular and autonomic abnormalities, as well as an impaired neurohemodynamic response to exercise. Objective: To test the hypothesis that normotensive individuals with a family history of hypertension present an impaired peripheral vascular resistance response to exercise. Methods: The study included 37 normotensive volunteers of both sexes who were sedentary, eutrophic, and nonsmokers, comprising 23 with (FH+