Navegando por Palavras-chave "Immunomodulatory activity"

Agora exibindo 1 - 1 de 1
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Gomesin acts in the immune system and promotes myeloid differentiation and monocyte/macrophage activation in mouse
    (Elsevier Science Inc, 2016) Buri, Marcus Vinicius [UNIFESP]; Dias, Carolina Carvalho [UNIFESP]; Barbosa, Christiano Marcello Vaz [UNIFESP]; Nogueira-Pedro, Amanda [UNIFESP]; Ribeiro-Filho, Antonio C.; Miranda, Antonio [UNIFESP]; Paredes-Gamero, Edgar Julian [UNIFESP]
    Due to the cytotoxic effect of antimicrobial peptides (AMP) against several microorganism and tumor cells has been proposed their association with the immune system. However, just a few reports have shown this relationship. In this study, mice were treated with gomesin, a beta-hairpin AMP that exhibit high cytotoxicity against bacterial and tumor cells. Different effects in the immune system were observed, such as, decrease of CD3(+) in T lymphocytes (Control: 17.7 +/- 1.4%