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- ItemAcesso aberto (Open Access)Efeito do adesivo butil-2-cianoacrilato em osteotomias e enxerto ósseo em coelhos: aspecto macroscópico e radiográfico(Sociedade Brasileira de Ortopedia e Traumatologia, 2012-10-01) Xavier, Mário Sérgio Viana; Leite, Vilnei Mattioli [UNIFESP]; UNIVÁS FACIMPA; Universidade Federal de São Paulo (UNIFESP)OBJECTIVE: To evaluate the effect of butyl-2-cyanoacrylate tissue adhesive in osteotomies and bone grafts, with regard to macroscopic and radiographic characteristics. METHODS: Forty-eight rabbits were used, randomly divided into four groups of 12 animals, with observation periods of two, four, eight and 16 weeks. Both thoracic limbs were operated in each animal and two osteotomies were performed in each of the radii, withdrawing a bone fragment (bone graft) of 1 cm in length. On one side, the bone graft was then replaced and a drop of adhesive was applied to each of the osteotomies. On the other side, the same procedure was performed without applying the adhesive. The rejection level for the nullity hypothesis was set at 0.05% or 5%. RESULTS: Blue marks were present in all the surgical specimens in which adhesive was applied. From the fourth week onwards, there was absence of movement of the bone grafts with adhesive and control. In group A, in the proximal osteotomies with adhesive, there was less deviation of the bone graft (p = 0.02). In group C, the union (p = 0.03) and the integration of the bone graft (p = 0.02) were better in the proximal osteotomies with adhesive. CONCLUSIONS: The adhesive was not completely metabolized within 16 weeks. There was clinical consolidation of the osteotomies within four weeks. The adhesive stabilized the bone graft within the first weeks and did not interfere with the consolidation of the osteotomies, or the integration of the bone graft in radiographic observations.
- ItemSomente MetadadadosEfeito do enxerto autologo de perichondrium costalis com butil-2-cianoacrilato em lesão provocada na cartilago articulares do joelho de coelhos(Universidade Federal de São Paulo (UNIFESP), 1997) Xavier, Mário Sergio Viana [UNIFESP]; Souza, Virgínio Cândido Tosta de [UNIFESP]
- ItemAcesso aberto (Open Access)Efeito do enxerto autólogo de pericôndrio costal com butil-2-cianoacrilato em lesão provocada na cartilagem articular do joelho de coelhos(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 1999-10-01) Xavier, Mário Sérgio Viana; Souza, Virgínio Cândido Tosta de; Gomes, Paulo de Oliveira [UNIFESP]; Corrêa, José Carlos; Novo, Neil Ferreira [UNIFESP]; Juliano, Yara [UNIFESP]; Faculdade de Ciências Médicas de Pouso Alegre; Universidade Federal de São Paulo (UNIFESP)The purpose of this study was to verify the effect of the perichondrium graft with butyl-2-cyanoacrylate in provoked injury in the articular cartilage of rabbit`s knee. Male adult animals were used, divided in 2 groups, called Group A and Group B, with 17 animals each. The Group A animals were reoperated in 4 weeks and the Group B animals in 8 weeks. A 2 cm fragment was taken out from the 7th costal cartilage from which the perichondrium was removed. Two osteo-cartilaginous cylinders were taken out from each medialis condyles of the femurs in the same animal. The articular cartilage of the cylinder was replaced in one side by the perichondrium with a thin layer of sticking-tissue in its external face and only the articular cartilage was removed from the other side. The cylinders were replaced in the femurs. Macroscopically, in Group A, most of the injuries which received the perichondrium were found completely covered with tissue and all the lesions without perichondrium were only partilly covered. In Group B, no macroscopic significant difference in the covering of the injuries was found. Statistically, There was no microscopical significant difference between the injuries with and without perichondrium of the Group A and Group B and neither groups A and B.