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- ItemSomente MetadadadosEfeitos de oito semanas de treinamento funcional sobre parâmetros bioquímicos, fisiológicos e psicobiológicos em surfistas amadores(Universidade Federal de São Paulo (UNIFESP), 2017-03-15) Andrade, Priscilla Lobo [UNIFESP]; Santos, Ronaldo Vagner Thomatieli dos [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Objective: Evaluate the effects of eight weeks of functional training on physical surfing capabilities, biochemical, physiological and psychobiological parameters in amateur surfers. Methodology: The sample consisted of 14 healthy male amateur surfers aged 20 and 40 years. The evaluations were performed at three times: before the start of the training program, 48 hours after and seven days later. The training lasted eight weeks with weekly frequency of three times a week. The athletic performance was evaluated by the power of rotation, power of the lower limbs, rotation flexibility, strength and endurance of the core muscles. Heart rate was monitored every second during every practice, and the Borg scale was used to describe the perceived exertion 15 minutes after the end of each exercise session. Serum glucose concentrations, triglycerides (TG), total cholesterol, high-density lipoprotein (HDL) and low- density lipoprotein (LDL) were evaluated by collecting 10 ml of venous blood. Regarding behavioral parameters were evaluated the mood, memory and sleep through the Brunel Mood Scale (BRUMS), Digit Span (numbers), Sleepiness Scale Epworth (ESS) and Pittsburg Scale, respectively. The normality of the data was verified by the Shapiro-Wilk's test. For the surfing capabilities physical tests were used Test T samples in pairs. For questionnaires of mood, sleep and memory were performed one-way ANOVA with post hoc Duncan. All data are expressed as mean and standard deviation. The level of significance was set at p ≤ 0.05. For this study we used the statistical software SPSS Statistcs 21. Results: There was a significant improvement in memory, daytime sleepiness index and physical surfing capabilities, except flexibility of rotation to the left. There were no changes in mood, sleep quality, blood lipids and blood glucose after eight weeks of training and seven days after. Conclusion: Functional training was effective to improve the physical surfing capabilities, aerobic fitness, memory and decrease daytime sleepiness index, however, did not cause changes in mood and quality of amateur surfers sleep or alter any plasma parameter.
- ItemSomente MetadadadosO Papel Do Exercício Físico Agudo E Crônico Na Lesão Renal Aguda Induzida Pela Sepse(Universidade Federal de São Paulo (UNIFESP), 2017-08-31) Hungaro, Talita Guerreiro Rodrigues [UNIFESP]; Araujo, Ronaldo De Carvalho [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Introduction: Hormone is a phenomenon where low levels of stress stimulate or regulate the molecular pathways positively and improve the organic capacity to withstand greater stress. This preconditioning can be achieved through different stimuli, including physical exercise. Previous work has demonstrated the preconditioning effect of physical exercise on injury or disease in different organs and systems, attenuating inflammatory responses and lung injury in endotoxemia, promoting adaptations, reducing injury and mortality during polymicrobial sepsis and preventing muscle damage in an experimental model of sepsis. Our study demonstrated that physical exercise is able to protect the kidney from nephrotoxicity caused by cisplatin by reducing levels of urea and creatinine, IL-1beta, IL-6, IL-10 and TNF-alpha in serum. Although several studies address chronic physical exercise, little is known about the role of acute exercise in disease development. Objectives: To verify the role of acute and chronic physical exercise in the treadmill in the endotoxemic response in renal injury. Method: C57BL / 6 male mice of 12 weeks were divided into 6 groups: 1- Sedentary control without LPS; 2- Sedentary with LPS; 3- Acute training without LPS; 4- Acute training with LPS; 5 - Chronic training without LPS and 6 - Chronic training with LPS. In the acute training the animals perform 1 session of physical exercise of 60 minutes. In chronic training the animals exercise 5 times a week, from Monday to Friday, 60 minutes each session, for 4 weeks. The training velocity was defined as 60% of the average of the maximum velocities reached, classifying the training as moderate. LPS induction was performed 24 hours after the end of the last exercise session. The responses of inflammatory or anti-inflammatory mediators were evaluated by elisas. Renal repercussion was measured by urea concentration, as well as by histological sections. Results: The dose of LPS applied intraperitoneally was 5mg / kg, with the serum extracted concentration tests were performed for the 6 experimental groups. There was a significant increase in urea concentration in all groups that received LPS when compared to those who did not, but there was no difference between the urea concentration in the groups trained with LPS and sedentary with LPS. Protein expression of IL-1beta showed no difference between groups, TNF-alpha presented expression only in the groups with LPS but without statistical difference. For IL-10, there was a difference between the sedentary + LPS groups and chronic LPS training, and the cytokine expression decreased in the trained group, contrary to the initial hypothesis. Partial conclusions: From the results obtained so far, it can be concluded that physical exercise was not able to prevent the inflammatory response caused by LPS infection.