Navegando por Palavras-chave "Breast implants"
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- ItemAcesso aberto (Open Access)Biocompatibilidade dos implantes de mama com superfície de espuma de silicone(Universidade Federal de São Paulo, 2021-07-14) Achilles, Rodrigo Bredariol [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; http://lattes.cnpq.br/9969803499258672; http://lattes.cnpq.br/6653322268021794; Universidade Federal de São Paulo (UNIFESP)Este estudo teve como objetivo estudar a biocompatibilidade do implante de mama com superfície de espuma de silicone, a partir da citotoxicidade, resposta inflamatória, colágeno produzido e compará-lo com outros dois tipos de implante disponíveis no mercado: nanotextura e microtextura. Para o teste de biocompatibilidade, foi empregado o teste de subcutâneo em roedores. Nesse estudo, foram utilizados 30 ratos machos (Rattus, norvegicus, albinos, Wistar) distribuídos em três grupos (10 animais por grupo), com 2 implantes em cada animal: o grupo 1 recebeu o implante com superfície de nanotextura, o grupo 2 com microtextura e o grupo 3 com espuma de silicone. Três animais de cada grupo foram sacrificados no 7º e 15º dias, e quatro animais sacrificados no 30º dia pós-implantação. Para o estudo in vitro, foram utilizados fibroblastos murinos L929 expostos às superfícies de espuma de silicone, micro- e macrotextura. Nessa avaliação, foram realizados os testes do MTT e Alamar Blue. No estudo in vitro, a espuma de silicone demonstrou potencial citotóxico em fibroblastos um pouco maior que as outras texturas nos primeiros dias pós-implantação, mas sem significância estatística no teste do Alamar Blue. Na avaliação microscópica, a nanotextura apresentou sinais de alta celularidade mesmo no 30º dia, a microtextura e a espuma de silicone apresentaram uma resolução da resposta inflamatória mais rápida, com amadurecimento precoce do tecido conjuntivo e diminuição da celularidade. A mesma resposta foi observada na coloração picro-sirius, com uma maturação mais rápida do colágeno no grupo da espuma de silicone. Desta forma, a espuma de silicone apresentou boa compatibilidade tantos nos ensaios in vitro como in vivo, mostrando-se uma boa opção de textura para implantes de mama.
- ItemAcesso aberto (Open Access)Evaluation of the rupture of silicone breast implants by mammography, ultrasonography and magnetic resonance imaging in asymptomatic patients: correlation with surgical findings(Associação Paulista de Medicina - APM, 2004-04-01) Scaranelo, Anabel Medeiros [UNIFESP]; Marques, Americo Ferreira [UNIFESP]; Smialowski, Elizabeth Brenda [UNIFESP]; Lederman, Henrique Manoel [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)CONTEXT: Different imaging methods can identify the integrity of breast implants and also the extent of possible silicone leakage. Mammography, ultrasonography and magnetic resonance imaging are often used to evaluate the integrity of breast implants, usually in patients that are symptomatic for rupture. A group of clinically asymptomatic patients was taken as a sample. These patients wanted to remove or change their breast implants for psychological or cosmetic reasons. OBJECTIVE: The purpose of this study was to compare the efficacy of mammography, sonography and magnetic resonance imaging in the detection of breast implant rupture in an asymptomatic population. TYPE OF STUDY: Prospective study. SETTING: Department of Diagnostic Imaging, Universidade de São Paulo, São Paulo, Brazil. METHODS: The participants were 44 asymptomatic patients who subsequently had implants surgically removed. Eighty-three implants were evaluated by both film-screen mammography and high-resolution sonography and 77 implants were evaluated by magnetic resonance imaging. The sensitivity and specificity of mammography, ultrasonography and magnetic resonance imaging were assessed using predetermined diagnostic criteria for implant rupture. All radiological signs were discussed and false positives and false negatives were retrospectively evaluated to identify the pitfalls in the investigations. RESULTS: The respective sensitivity and specificity of mammography were 20% and 89%; sonography, 30% and 81%; and magnetic resonance imaging, 64% and 77%. The differences between patients with breast implants for cosmetic and oncological reasons were discussed. CONCLUSIONS: Our experience suggests that magnetic resonance imaging seems to be the best imaging method on its own for the evaluation of rupturing among asymptomatic patients.
- ItemSomente MetadadadosPatient-reported outcomes measured by BREAST-Q after implant-based breast reconstruction: A cross-sectional controlled study in Brazilian patients(Churchill Livingstone, 2017) Aguiar, Isabella de Carvalho [UNIFESP]; Veiga, Daniela Francescato [UNIFESP]; Marques, Thaline Figueiredo; Novo, Neil Ferreira; Sabino Neto, Miguel [UNIFESP]; Ferreira, Lydia Masako [UNIFESP]Objective: The purpose of this study was to assess patient-reported outcomes of breast reconstruction with implants, using the BREAST-Q, in the late postoperative period. Materials and methods: A total of 114 women previously operated due to breast cancer, in the late postoperative period (range 6-24 months) were enrolled in this cross-sectional study, and were allocated to either the mastectomy group (MG, n = 57) or reconstruction group (RG, n = 57). Patients in MG and RG, respectively, completed the Brazilian versions of Mastectomy and Reconstruction Modules of the BREAST-Q. Results: The mean age of patients was 46.6 and 44.3 years in MG and RG, respectively. All patients underwent chemotherapy and 6% and 11% of patients underwent radiotherapy in MG and RG, respectively. Patients in the RG reported higher satisfaction with surgical outcome (P < 0.0001). However, no significant between-group differences were found in physical and sexual well-being, or satisfaction with the plastic surgeon, medical team, and office staff. Conclusion: Breast reconstruction with implants increased patient satisfaction with the surgical outcome, but did not influence patients' physical and sexual well-being or their satisfaction with the treatment received. (C) 2016 Elsevier Ltd. All rights reserved.
- ItemAcesso aberto (Open Access)Treatment of bilateral mammary ptosis and pectus excavatum through the same incision in one surgical stage(Associação Paulista de Medicina - APM, 2012-01-01) Rocha, Fernando Passos da [UNIFESP]; Pires, Jefferson André; Torres, Vinicius Franchini; Fagundes, Djalma José [UNIFESP]; Universidade Católica de Pelotas; Universidade Federal de Pelotas; Universidade Federal de São Paulo (UNIFESP)CONTEXT: Congenital deformities of the anterior thoracic wall are characterized by unusual development of the costal cartilages. All these medical conditions are frequently associated with a variety of breast deformities. Several surgical techniques have been described for correcting them, going from sternochondroplasty to, nowadays, minimally invasive techniques and silicone prosthesis implantation. CASE REPORT: The present article reports the case of a young female patient who presented bilateral mammary ptosis and moderate pectus excavatum that caused a protrusion between the eighth and the tenth ribs and consequent esthetic disharmony. The proposed surgical treatment included not only subglandular breast implants of polyurethane, but also resection of part of the rib cartilage and a bone segment from the eighth, ninth and tenth ribs by means of a single submammary incision in order to make the scar minimally visible. Correction through a single incision benefited the patient and provided an excellent esthetic result. CONCLUSIONS: The techniques used to repair bilateral mammary ptosis and pectus excavatum by plastic and thoracic surgery teams, respectively, have been shown to be efficient for correcting both deformities. An excellent esthetic and functional result was obtained, with consequent reestablishment of the patient's self-esteem.