Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy

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dc.contributor.authorMartinho, Fernanda Louise [UNIFESP]
dc.contributor.authorZonato, Adriane Iurck [UNIFESP]
dc.contributor.authorBittencourt, Lia Rita Azeredo [UNIFESP]
dc.contributor.authorSoares, Maria Claudia Mattos [UNIFESP]
dc.contributor.authorSilva, Rogério Fernandes Nunes da [UNIFESP]
dc.contributor.authorGregório, Luiz Carlos [UNIFESP]
dc.contributor.authorTufik, Sergio [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2015-06-14T13:36:22Z
dc.date.available2015-06-14T13:36:22Z
dc.date.issued2006-08-01
dc.description.abstractThe physiopathology of obstructive sleep apnea-hypopnea syndrome (OSAHS) is multifactorial and obesity has been shown to be one of the main factors correlated with its occurrence. In obese patients with anatomical alterations of the upper airways it is often difficult to predict success for surgical correction since obesity is a limiting factor. Therefore, the aim of the present study was to evaluate the results of tonsillectomy in a specific group of patients, i.e., obese OSAHS patients with tonsil hypertrophy. Seven OSAHS patients with moderate obesity with obstructive palatine tonsil hypertrophy were submitted to tonsillectomy. All patients were submitted to pre- and postoperative appraisal of body mass index, otorhinolaryngology examination and polysomnography. Patients' average age was 36.4 ± 10.3 years and average preoperative body mass index was 36.6 ± 6.3 kg/m². Postoperative weight did not differ significantly from preoperative weight (P = 0.27). Average preoperative apnea and hypopnea index (AHI) was 81 ± 26/h and postoperative AHI was 23 ± 18/h (P = 0.0005). Average preoperative minimum oxyhemoglobin saturation (SaO2 min) was 69 ± 14% and the postoperative value was 83 ± 3% (P = 0.038). In relation to AHI, 6 (86%) of the 7 patients studied showed a reduction of 50% in relation to preoperative level and of these, 4 (57%) presented AHI of less than 20%. Only one patient presented a reduction of less than 50% in AHI, but even so showed improved SaO2 min. Tonsillectomy treatment for OSAHS in obese patients with obstructive palatine tonsil hypertrophy caused a significant reduction in AHI, with improvement in SaO2 min. This procedure could be eventually considered as an option of treatment for obese OSAHS patients with significant tonsil hypertrophy when continuous positive air pressure therapy is not possible as the first choice of treatment.en
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Departamento de Otorrinolaringologia
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Departamento de Psicobiologia Instituto do Sono
dc.description.affiliationUnifespUNIFESP, Depto. de Otorrinolaringologia
dc.description.affiliationUnifespUNIFESP, Depto. de Psicobiologia Instituto do Sono
dc.description.sourceSciELO
dc.format.extent1137-1142
dc.identifierhttps://dx.doi.org/10.1590/S0100-879X2006000800017
dc.identifier.citationBrazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 39, n. 8, p. 1137-1142, 2006.
dc.identifier.doi10.1590/S0100-879X2006000800017
dc.identifier.fileS0100-879X2006000800017.pdf
dc.identifier.issn0100-879X
dc.identifier.scieloS0100-879X2006000800017
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/3188
dc.identifier.wosWOS:000239936900017
dc.language.isoeng
dc.publisherAssociação Brasileira de Divulgação Científica
dc.relation.ispartofBrazilian Journal of Medical and Biological Research
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSleep apnea syndromeen
dc.subjectObesityen
dc.subjectSurgeryen
dc.subjectTonsillectomyen
dc.subjectApnea and hypopnea indexen
dc.titleObese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomyen
dc.typeinfo:eu-repo/semantics/article
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