Desenvolvimento de xampu sólido com pigmentos naturais: caracterização físico-química, microbiológica e análise da atividade antioxidante
Data
2022-05-20
Autores
Costa, Stephanie Fabrícia Francisco 
Orientadores
Braga, Anna Rafaela Cavalcante
Tipo
Dissertação de mestrado
Título da Revista
ISSN da Revista
Título de Volume
Resumo
O desenvolvimento de cosméticos formulados com ingredientes naturais está em ascensão e os xampus sólidos se apresentam como alternativa natural e ecológica que vem ganhando espaço na indústria cosmética. Compostos bioativos encontrados na natureza têm se destacado por exibirem propriedades promotoras de saúde, como atividade antioxidante e anti-inflamatória. Dentre os recursos naturais, a cianobactéria Spirulina (Arthrospira platensis) tem recebido destaque como possível ingrediente em diferentes formulações biotecnológicas por seu alto teor proteico e de compostos bioativos, relacionados à ação antioxidante, anti-inflamatória, antimicrobiana e anti-idade. Assim sendo, tanto a biomassa da cianobactéria quanto os bioativos que a compõe podem ser considerados potenciais ingredientes nas mais diferentes indústrias, desde a indústria de alimentos, energias renováveis e, mais recentemente, sua aplicação em formulações cosméticas. Considerando o exposto, o objetivo desse trabalho é desenvolver formulações cosméticas do tipo xampus sólidos usando pigmentos naturais derivados de Spirulina, que forneçam cor e propriedades promotoras de saúde. Além disso, foi realizado a caracterização físico-química e microbiológica, análise da estabilidade da cor e da atividade biológica dos bioprodutos elaborados. Para isso, foram elaborados quatro xampus sólidos: xampu controle (A), sem adição de pigmentos, xampu contendo 1% (m/m) de C-FC (B), xampu com 5% (m/m) de biomassa de Spirulina (C) e com 5% (m/m) de biomassa residual de Spirulina (D) (obtida após extração da C-FC). A caracterização físico-química realizada apresentou resultados dentro das faixas preconizadas pela Agência Nacional de Vigilância Sanitária (ANVISA) para todos os parâmetros avaliados. Os resultados da análise microbiológica indicaram que todas as amostras foram seguras e produzidas de maneira sanitária. Todos os xampus produzidos adicionados de pigmentos apresentaram atividade antioxidante e teor de compostos fenólicos maior do que o xampu controle. Porém, a formulação produzida com a biomassa de Spirulina (C) apresentou maior estabilidade em sua ação pigmentante e o mesmo aconteceu com a atividade antioxidante considerando os dois métodos estudados na avaliação deste parâmetro, durante o período avaliado.
The development of cosmetics formulated with natural ingredients is on the rise and solid shampoos are presented as a natural and ecological alternative that has been gaining ground in the cosmetic industry. The bioactive compounds found in nature have exhibited properties that promote antioxidant and antiinflammatory activity. Among the natural resources, the cyanobacterium Spirulina (Arthrospira platensis) is a possible ingredient in different biotechnological formulations due to its high protein content and bioactive compounds. Also, among the components of Spirulina biomass, the pigment Cphycocyanin (CPC) is the main natural phycobiliprotein that has, according to the literature, antioxidant, antiinflammatory, antimicrobial, and antiaging properties. Therefore, the biomass of cyanobacteria and the CPC, which composes, is considered potential ingredients in various industries, such as the food industry, renewable energy, and, more recently, its application in cosmetics formulas. Considering the above, this work aims to develop cosmetic formulations such as solid shampoos using natural pigments derived from Spirulina, which provide color and healthpromoting properties. In addition, physicalchemical and microbiological characterization, analysis of color stability and biological activity of the produced bioproducts were carried out. As a result, four solid shampoos were prepared: control shampoo (A), without the addition of pigments containing 1% (w/w) of CPC (B), shampoo with 5% (w/w) Spirulina biomass (C) and with 5% (w/w) of residual Spirulina biomass (D) (obtained after extracting the CPC). The physicalchemical characterization presented results within the ranges determined by the Agência Nacional de Vigilância Sanitária (ANVISA) for all evaluated parameters. The results of the microbiological analysis indicated that all samples are considered safe and sanitary. All shampoos produced with the addition of pigments exhibited higher antioxidant activity and phenolic compounds content than the control shampoo. However, the formulation produced with Spirulina biomass (C) showed greater stability in its pigmenting action and the same happened with the antioxidant activity considering the two methods studied in the evaluation of this parameter, during the evaluated period.
The development of cosmetics formulated with natural ingredients is on the rise and solid shampoos are presented as a natural and ecological alternative that has been gaining ground in the cosmetic industry. The bioactive compounds found in nature have exhibited properties that promote antioxidant and antiinflammatory activity. Among the natural resources, the cyanobacterium Spirulina (Arthrospira platensis) is a possible ingredient in different biotechnological formulations due to its high protein content and bioactive compounds. Also, among the components of Spirulina biomass, the pigment Cphycocyanin (CPC) is the main natural phycobiliprotein that has, according to the literature, antioxidant, antiinflammatory, antimicrobial, and antiaging properties. Therefore, the biomass of cyanobacteria and the CPC, which composes, is considered potential ingredients in various industries, such as the food industry, renewable energy, and, more recently, its application in cosmetics formulas. Considering the above, this work aims to develop cosmetic formulations such as solid shampoos using natural pigments derived from Spirulina, which provide color and healthpromoting properties. In addition, physicalchemical and microbiological characterization, analysis of color stability and biological activity of the produced bioproducts were carried out. As a result, four solid shampoos were prepared: control shampoo (A), without the addition of pigments containing 1% (w/w) of CPC (B), shampoo with 5% (w/w) Spirulina biomass (C) and with 5% (w/w) of residual Spirulina biomass (D) (obtained after extracting the CPC). The physicalchemical characterization presented results within the ranges determined by the Agência Nacional de Vigilância Sanitária (ANVISA) for all evaluated parameters. The results of the microbiological analysis indicated that all samples are considered safe and sanitary. All shampoos produced with the addition of pigments exhibited higher antioxidant activity and phenolic compounds content than the control shampoo. However, the formulation produced with Spirulina biomass (C) showed greater stability in its pigmenting action and the same happened with the antioxidant activity considering the two methods studied in the evaluation of this parameter, during the evaluated period.
Descrição
Citação
COSTA, Stephanie Fabrícia Francisco. Desenvolvimento de xampu sólido com pigmentos naturais: caracterização físico-química, microbiológica e análise da atividade antioxidante. 2022. 70 f. Dissertação (Mestrado em Bioprodutos e Bioprocessos) - Instituto de Saúde e Sociedade, Universidade Federal de São Paulo, Santos, 2022.