Avaliação Dos Marcadores Hematológicos Como Possíveis Fatores Prognósticos No Câncer De Cabeça E Pescoço
Data
2018-05-31
Autores
Padua, Tiago Costa De 
Orientadores
Baiocchi, Otavio Cesar Carvalho Guimaraes
Tipo
Dissertação de mestrado
Título da Revista
ISSN da Revista
Título de Volume
Resumo
Valor Prognóstico Dos Marcadores Hematológicos Em Cabeça E Pescoço Escamoso Carcinoma De Células: Experiência De Um Hospital Público Brasileiro Finalidade / Objetivo (S): O Objetivo De Nosso Estudo Foi Investigar A Papel Prognóstico Potencial De Marcadores Hematológicos Pré-Tratamento, Neutrófilos A Rácio Linfocitário (Nlr) E Relação Plaqueta / Linfócitos (Plr), Em Doentes Com Carcinoma Espinocelular De Cabeça E Pescoço (Hnscc) Tratado Com Quimiorradioterapia (Crt). Materiais / Métodos: Analisamos Retrospectivamente Prontuários De 52 Pacientes Com Diagnóstico De Cec De Cabeça E Pescoço E Tratados Com Trc Definitiva Em Nosso Instituição. Pré-Tratamento Nlr E Plr ""Foram Calculados Retrospectivamente E Investigado Para Correlação Com A Sobrevivência Global (Os) Usando O Kaplan-Meier Método. A Análise Univariada Para Variáveis ""Categóricas E Descritivas Também Foi Realizado. Resultados: Na População Geral, A Mediana Do Os (Mos) Foi De 28 Meses. Em Análise Univariada, Estágio Tumoral (T2 Vs T4a- T4b), Estágio No
Prognostic Value Of Hematologic Markers In Head And Neck Squamous Cell Carcinoma: Experience Of A Brazilian Public Hospital Purpose/Objective(S): The Purpose Of Our Study Was To Investigate The Potential Prognostic Role Of Pretreatment Hematologic Markers, Neutrophil To Lymphocyte Ratio (Nlr) And Platelet To Lymphocyte Ratio (Plr), In Patients With Head And Neck Squamous Cell Carcinoma (Hnscc) Treated With Chemoradiotherapy (Crt). Materials/Methods: We Retrospectively Analyzed Medical Records Of 52 Patients Diagnosed With Hnscc And Treated With Definitive Crt At Our Institution. Pretreatment Nlr And Plr Were Retrospectively Calculated And Investigated For Correlation With Overall Survival (Os) Using The Kaplan-Meier Method. Univariate Analysis For Categorical And Descriptive Variables Was Also Performed. Results: In The Overall Population, Median Os (Mos) Was 28 Months. In Univariate Analysis, Tumor Stage (T2 Vs T4a- T4b), Nodal Stage (N0 Vs N2 Or N3) And Plr Were Associated With Improved Os (Hr 1.003; 95% Ci
Prognostic Value Of Hematologic Markers In Head And Neck Squamous Cell Carcinoma: Experience Of A Brazilian Public Hospital Purpose/Objective(S): The Purpose Of Our Study Was To Investigate The Potential Prognostic Role Of Pretreatment Hematologic Markers, Neutrophil To Lymphocyte Ratio (Nlr) And Platelet To Lymphocyte Ratio (Plr), In Patients With Head And Neck Squamous Cell Carcinoma (Hnscc) Treated With Chemoradiotherapy (Crt). Materials/Methods: We Retrospectively Analyzed Medical Records Of 52 Patients Diagnosed With Hnscc And Treated With Definitive Crt At Our Institution. Pretreatment Nlr And Plr Were Retrospectively Calculated And Investigated For Correlation With Overall Survival (Os) Using The Kaplan-Meier Method. Univariate Analysis For Categorical And Descriptive Variables Was Also Performed. Results: In The Overall Population, Median Os (Mos) Was 28 Months. In Univariate Analysis, Tumor Stage (T2 Vs T4a- T4b), Nodal Stage (N0 Vs N2 Or N3) And Plr Were Associated With Improved Os (Hr 1.003; 95% Ci