Peripheral nerve regeneration with conduits: use of vein tubes

dc.contributor.authorSabongi, Rodrigo Guerra [UNIFESP]
dc.contributor.authorFernandes, Marcela [UNIFESP]
dc.contributor.authorSantos, João Baptista Gomes dos [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:40:17Z
dc.date.available2016-01-24T14:40:17Z
dc.date.issued2015-04-01
dc.description.abstractTreatment of peripheral nerve injuries remains a challenge to modern medicine due to the complexity of the neurobiological nerve regenerating process. There is a greater challenge when the transected nerve ends are not amenable to primary end-to-end tensionless neurorraphy. When facing a segmental nerve defect, great effort has been made. to develop an alternative to the autologous nerve graft in order to circumvent morbidity at donor site, such as neuroma formation, scarring and permanent loss of function. Tubolization techniques have been developed to bridge nerve gaps and have been extensively studied in numerous:experimental and clinical trials. the use of a conduit intends to act as a vehicle for moderation and modulation of the cellular and molecular ambience for nerve regeneration. Among several conduits, vein tubes were validated for clinical application with improving outcomes over the Years. This article aims to address the investigation and treatment of segmental nerve injury and draw the current panorama on the use of vein tubes as an autogenous nerve conduit.en
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Dept Orthoped & Traumatol, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Dept Orthoped & Traumatol, Div Hand Surg, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Dept Orthoped & Traumatol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Dept Orthoped & Traumatol, Div Hand Surg, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent529-533
dc.identifierhttp://dx.doi.org/10.4103/1673-5374.155428
dc.identifier.citationNeural Regeneration Research. Shenyang: Shenyang Editorial Dept Neural Regeneration Res, v. 10, n. 4, p. 529-533, 2015.
dc.identifier.doi10.4103/1673-5374.155428
dc.identifier.issn1673-5374
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/38924
dc.identifier.wosWOS:000354156200004
dc.language.isoeng
dc.publisherShenyang Editorial Dept Neural Regeneration Res
dc.relation.ispartofNeural Regeneration Research
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectperipheral nerve injuryen
dc.subjectnerve graften
dc.subjectnerve conduiten
dc.subjectWallerian degenerationen
dc.subjectneurotrophic factorsen
dc.subjectveinsen
dc.subjectautograftsen
dc.subjectnerve regenerationen
dc.titlePeripheral nerve regeneration with conduits: use of vein tubesen
dc.typeinfo:eu-repo/semantics/article
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