The validation of the Z-Scan technique for the determination of plasma glucose

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dc.contributor.authorAlves, Sarah I. [UNIFESP]
dc.contributor.authorSilva, Elaine A. O. [UNIFESP]
dc.contributor.authorCosta, Simone S.
dc.contributor.authorSonego, Denise R. N. [UNIFESP]
dc.contributor.authorHallack, Maira L. [UNIFESP]
dc.contributor.authorCoppini, Ornela L. [UNIFESP]
dc.contributor.authorRowies, Fernanda [UNIFESP]
dc.contributor.authorAzzalis, Ligia A. [UNIFESP]
dc.contributor.authorJunqueira, Virginia B. C. [UNIFESP]
dc.contributor.authorPereira, Edimar C. [UNIFESP]
dc.contributor.authorRocha, Katya C. [UNIFESP]
dc.contributor.authorFonseca, Fernando L. A. [UNIFESP]
dc.contributor.authorCosta, MFPCM
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:31:05Z
dc.date.available2016-01-24T14:31:05Z
dc.date.issued2013-01-01
dc.description.abstractGlucose is the main energy source for the human body. the concentration of blood glucose is regulated by several hormones including both antagonists: insulin and glucagon. the quantification of glucose in the blood is used for diagnosing metabolic disorders of carbohydrates, such as diabetes, idiopathic hypoglycemia and pancreatic diseases. Currently, the methodology used for this determination is the enzymatic colorimetric with spectrophotometric. This study aimed to validate the use of measurements of nonlinear optical properties of plasma glucose via the Z-Scan technique. for this we used samples of calibrator patterns that simulate commercial samples of patients (ELITech(C)). Besides calibrators, serum glucose levels within acceptable reference values (normal control serum - Brazilian Society of Clinical Pathology and Laboratory Medicine) and also overestimated (pathological control serum - Brazilian Society of Clinical Pathology and Laboratory Medicine) were used in the methodology proposal. Calibrator dilutions were performed and determined by the Z-Scan technique for the preparation of calibration curve. in conclusion, Z-Scan method can be used to determinate glucose levels in biological samples with enzymatic colorimetric reaction and also to apply the same quality control parameters used in biochemistry clinical.en
dc.description.affiliationUniversidade Federal de São Paulo, Inst Ciencias Ambientais Quim & Farmaceut, Diadema, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Inst Ciencias Ambientais Quim & Farmaceut, ICAQF, Diadema, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent6
dc.identifierhttp://dx.doi.org/10.1117/12.2025994
dc.identifier.citation8th Iberoamerican Optics Meeting and 11th Latin American Meeting On Optics, Lasers, and Applications. Bellingham: Spie-int Soc Optical Engineering, v. 8785, 6 p., 2013.
dc.identifier.doi10.1117/12.2025994
dc.identifier.issn0277-786X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/35839
dc.identifier.wosWOS:000328616100016
dc.language.isoeng
dc.publisherSpie-int Soc Optical Engineering
dc.relation.ispartof8th Iberoamerican Optics Meeting and 11th Latin American Meeting On Optics, Lasers, and Applications
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectZ-Scanen
dc.subjectNonlinear Opticsen
dc.subjectBiomedical Opticsen
dc.subjectGlucoseen
dc.subjectCalibration Curveen
dc.titleThe validation of the Z-Scan technique for the determination of plasma glucoseen
dc.typeinfo:eu-repo/semantics/conferenceObject
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