Evaluation of Placental Volume at 7-10+6 Weeks of Pregnancy by 3D-Sonography
Data
2009-07-01
Autores
Nardozza, L. M. M. 
Nowak, P. M.
Araujo Junior, E.
Guimaraes Filho, H. A.
Rolo, L. C.
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Artigo
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Título de Volume
Resumo
The aim of the study was to establish normative data for placental volume (PV) at 7-10+6 weeks of gestation using three-dimensional ultrasound (3DUS). the cross-sectional study involved 70 healthy pregnancies between 7 and 11 weeks. the VOCAL (Virtual Organ Computer-aided Analysis) method with a 30 rotation angle and six planes was used for volumetric calculations. Regression models were constructed to assess the correlation between PV and crown-rump length (CRL) adjusted by the determination coefficient (R(2)). the method proposed by Royston and Wright was used to establish the 2.5th; 10th; 50th; 90th and 97.5th percentiles (percentile = mean + K x SD). the intraclass correlation coefficient (ICC), Bland-Altman graphs and Student's paired t-tests were used to assess intra- and interobserver variability. PV ranged from 1.7 to 42.6 cm(3), with a mean of 13.6 cm(3) ( 9A cm(3)). There was a strong correlation between PV and CRL; the exponential equation was the model that best expressed the correlation between them (R(2) = 0.76). for CRL between 9 and 40 mm, the mean PV increased 10.5 times, while CRL increased only 4.4 times. Inter- and intraobserver correlation were excellent (ICC=0.979 and 0.971, respectively). Bland-Altman graphs indicated a good reproducibility with a mean intraobserver and interobserver difference of 0.2 cm(3) (95% CI: -0.7-1.2 cm(3)) and -0.2 cm(3) (95% CI: -1.3-0.9 cm(3)), respectively. Reference limits were generated for first trimester PV assessed by 3DUS using the VOCAL method. There is a strong correlation between PV and CRL Placental volume obtained through this method was highly reproducible. Crown Copyright (C) 2009 Published by Elsevier B.V. All rights reserved.
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Citação
Placenta. London: W B Saunders Co Ltd, v. 30, n. 7, p. 585-589, 2009.