Adult-onset acne: prevalence, impact, and management challenges

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dc.citation.volume11
dc.contributor.authorRocha, Marco A. [UNIFESP]
dc.contributor.authorBagatin, Edileia [UNIFESP]
dc.coverageAlbany
dc.date.accessioned2020-07-02T18:52:06Z
dc.date.available2020-07-02T18:52:06Z
dc.date.issued2018
dc.description.abstractAcne is a multifactorial and inflammatory disease of pilosebaceous follicles, which affects most adolescents. Recent epidemiological data revealed a difference in adults affected by this disease. Women have a high prevalence and incidence when compared with men, especially after 25 years of age. In contrast to what was initially thought, most of these patients do not present endocrinopathy capable of leading to the development of the lesions. When present, polycystic ovarian syndrome is the main cause. However, in these cases, acne is rarely the only dermatological manifestationen
dc.description.abstracthirsutism and acanthosis nigricans are often present. The majority of the normoandrogenic acne patients present a history since adolescence, but in many cases the lesion distribution and intensity change with time. There is often a typical localization of the lesions in the lower third of the face and lateral region of the neck. Another interesting feature is related to the impact on quality of life (QoL), which is always intense. Often there are signs of depression, even when the lesions are mild. As most adult patients are women, in addition to the conventional options, there is also hormone treatment. Combined oral contraceptives and spironolactone are good options. Knowing more about the particularities in etiopathogenesis, impact on QoL, and specific treatment options is important to all dermatologists who face the challenge of treating acne in adults.en
dc.description.affiliationUniv Fed Sao Paulo, Paulista Med Sch, Rua Eugenio Bettarello 55 Ap 134B, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Paulista Med Sch, Rua Eugenio Bettarello 55 Ap 134B, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent59-69
dc.identifierhttp://dx.doi.org/10.2147/CCID.S137794
dc.identifier.citationClinical Cosmetic And Investigational Dermatology. Albany, v. 11, p. 59-69, 2018.
dc.identifier.doi10.2147/CCID.S137794
dc.identifier.fileWOS000424486000001.pdf
dc.identifier.issn1178-7015
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/53878
dc.identifier.wosWOS:000424486000001
dc.language.isoeng
dc.publisherDove Medical Press Ltd
dc.relation.ispartofClinical Cosmetic And Investigational Dermatology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectadulten
dc.subjectacneen
dc.subjecthormonalen
dc.subjectfemaleen
dc.titleAdult-onset acne: prevalence, impact, and management challengesen
dc.typeinfo:eu-repo/semantics/article
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