Comparative study between ultrasound-guided fine needle aspiration cytology of axillary lymph nodes and sentinel lymph node histopathology in early-stage breast cancer

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dc.citation.issue5
dc.citation.volume13
dc.contributor.authorCardoso-Coelho, Livio Portela
dc.contributor.authorBorges, Rafael Soares
dc.contributor.authorAlencar, Airlane Pereira
dc.contributor.authorCardoso-Campos-Verdes, Larysse Maira
dc.contributor.authorda Silva-Sampai, Joao Paulo
dc.contributor.authorBorges, Umbelina Soares
dc.contributor.authorGebrim, Luiz Henrique [UNIFESP]
dc.contributor.authorda Silva, Benedito Borges
dc.coverageAthens
dc.date.accessioned2020-07-13T11:53:25Z
dc.date.available2020-07-13T11:53:25Z
dc.date.issued2017
dc.description.abstractThe replacement of sentinel lymph node biopsy (SNB) by ultrasound-guided fine-needle aspiration (US-guided FNA) cytology of axillary lymph nodes is controversial, despite the simplicity and reduced cost of the latter. In the present study, US-guided FNA was performed in 27 patients with early-stage breast cancer for comparison with SNB. Data were analyzed by calculation of sample proportions. Tumor subtypes included invasive ductal carcinoma (85%), invasive lobular carcinoma (7%), and tubular and metaplastic carcinoma (4%). FNA had a sensitivity of 45%, specificity of 100%, positive predictive value of 100% and a negative predictive value of 73%. Axillary lymph node cytology obtained by US guided-FNA in patients with breast cancer had a specificity similar to that of sentinel lymph node histopathology in the presence of axillary node metastases. However, when lymph node cytology is negative, it does not exclude the existence of metastatic implants, due to its low sensitivity in comparison to sentinel lymph node histopathology.en
dc.description.affiliationUniv Fed Piaui, Postgrad Sci & Hlth Program, 2280 Ave Frei Serafim, BR-64001020 Teresina, PI, Brazil
dc.description.affiliationGetulio Vargas Hosp, Breast Disorder Unit, 2280 Ave Frei Serafim, BR-64001020 Teresina, PI, Brazil
dc.description.affiliationUniv Sao Paulo, Dept Stat, BR-05508220 Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Mastol, BR-04024002 Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Mastol, BR-04024002 Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent3299-3302
dc.identifierhttp://dx.doi.org/10.3892/ol.2017.5817
dc.identifier.citationOncology Letters. Athens, v. 13, n. 5, p. 3299-3302, 2017.
dc.identifier.doi10.3892/ol.2017.5817
dc.identifier.issn1792-1074
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/54607
dc.identifier.wosWOS:000401129800062
dc.language.isoeng
dc.publisherSpandidos Publ Ltd
dc.relation.ispartofOncology Letters
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectbreast canceren
dc.subjectaxillary lymph nodeen
dc.subjectsentinel lymph nodeen
dc.subjectfine-needle aspiration biopsyen
dc.titleComparative study between ultrasound-guided fine needle aspiration cytology of axillary lymph nodes and sentinel lymph node histopathology in early-stage breast canceren
dc.typeinfo:eu-repo/semantics/article
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