Ultrasonographic assessment of thyroid volume in oldest-old individuals

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dc.citation.issue3
dc.citation.volume61
dc.contributor.authorDuarte, Glaucia Cruzes [UNIFESP]
dc.contributor.authorQuirino Araujo, Lara Miguel [UNIFESP]
dc.contributor.authorMagalhaes Filho, Felix [UNIFESP]
dc.contributor.authorAlmada Filho, Clineu Mello [UNIFESP]
dc.contributor.authorCendoroglo, Maysa Seabra [UNIFESP]
dc.coverageRio De Janeiro, Rj
dc.date.accessioned2020-07-13T11:53:18Z
dc.date.available2020-07-13T11:53:18Z
dc.date.issued2017
dc.description.abstractObjective: The aim of this study was to describe the relationship between thyroid volume and age, gender, anthropometric characteristics, and echogenicity in oldest-old subjects in an iodine-sufficient area. Subjects and methods: The study included 81 independent elderly individuals aged >= 80 years (65 [80.2%] women). We determined these individuals' anthropometric characteristics, body mass index (BMI), and lean body mass, as well as thyroid volume and echogenicity by ultrasonography. Results: We observed that octogenarians and nonagenarians had different profiles of thyroid echogenicity. The volume of the thyroid was smaller in nonagenarians than octogenarians (p = 0.012, r = 0.176), and subjects aged 80-89 years had more often hypoechoic glands than those aged >= 90 years (p = 0.01 versus 0.602). Conclusion: The identification of ultrasonographic differences in oldest-old individuals will contribute to establishing preclinical markers, such as echogenicity, to identify individuals at risk of developing autoimmune thyroid disease. Future prospective studies should identify if 80-89-year-old individuals with hypoechoic glands progress to hypothyroidism, and if the absence of changes in echogenicity (i.e. a normal thyroid parenchyma) would have a positive impact on longevity among nonagenarians.en
dc.description.affiliationUniv Fed Sao Paulo Unifesp, Disciplina Geriatria & Gerontol, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo Unifesp, Disciplina Geriatria & Gerontol, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCoordenacao de Aperfeicoamento de Pessoal de Nivel Superior (Capes)
dc.description.sponsorshipFundacao de Amparo a Pesquisa do Estado de Sao Paulo (Fapesp)
dc.format.extent269-275
dc.identifierhttp://dx.doi.org/10.1590/2359-3997000000223
dc.identifier.citationArchives Of Endocrinology Metabolism. Rio De Janeiro, Rj, v. 61, n. 3, p. 269-275, 2017.
dc.identifier.doi10.1590/2359-3997000000223
dc.identifier.fileS2359-39972017000300269.pdf
dc.identifier.issn2359-3997
dc.identifier.scieloS2359-39972017000300269
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/54529
dc.identifier.wosWOS:000405404300011
dc.language.isoeng
dc.publisherSbem-Soc Brasil Endocrinologia & Metabologia
dc.relation.ispartofArchives Of Endocrinology Metabolism
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectThyroid diseasesen
dc.subjectthyroiditisen
dc.subjectautoimmuneen
dc.subjectultrasonographyen
dc.subjectoldest olden
dc.titleUltrasonographic assessment of thyroid volume in oldest-old individualsen
dc.typeinfo:eu-repo/semantics/article
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