Stress-induced endocrine response and anxiety: the effects of comfort food in rats

Página do item simplificado
dc.contributor.authorOrtolani, Daniela [UNIFESP]
dc.contributor.authorGarcia, Marcia Carvalho [UNIFESP]
dc.contributor.authorMelo-Thomas, Liana [UNIFESP]
dc.contributor.authorSpadari-Bratfisch, Regina Celia [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:37:17Z
dc.date.available2016-01-24T14:37:17Z
dc.date.issued2014-05-01
dc.description.abstractThe long-term effects of comfort food in an anxiogenic model of stress have yet to be analyzed. Here, we evaluated behavioral, endocrine and metabolic parameters in rats submitted or not to chronic unpredictable mild stress (CUMS), with access to commercial chow alone or to commercial chow and comfort food. Stress did not alter the preference for comfort food but decreased food intake. in the elevated plus-maze (EPM) test, stressed rats were less likely to enter/remain in the open arms, as well as being more likely to enter/remain in the closed arms, than were control rats, both conditions being more pronounced in the rats given access to comfort food. in the open field test, stress decreased the time spent in the centre, independent of diet; neither stress nor diet affected the number of crossing, rearing or grooming episodes. the stress-induced increase in serum corticosterone was attenuated in rats given access to comfort food. Serum concentration of triglycerides were unaffected by stress or diet, although access to comfort food increased total cholesterol and glucose. It is concluded that CUMS has an anorexigenic effect. Chronic stress and comfort food ingestion induced an anxiogenic profile although comfort food attenuated the endocrine stress response. the present data indicate that the combination of stress and access to comfort food, common aspects of modern life, may constitute a link among stress, feeding behavior and anxiety.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Biosci, Santos, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Biosci, Santos, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent211-218
dc.identifierhttp://dx.doi.org/10.3109/10253890.2014.898059
dc.identifier.citationStress-the International Journal On the Biology of Stress. London: Informa Healthcare, v. 17, n. 3, p. 211-218, 2014.
dc.identifier.doi10.3109/10253890.2014.898059
dc.identifier.issn1025-3890
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/37761
dc.identifier.wosWOS:000334940500002
dc.language.isoeng
dc.publisherInforma Healthcare
dc.relation.ispartofStress-the International Journal On the Biology of Stress
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://informahealthcare.com/userimages/ContentEditor/1255620309227/Copyright_And_Permissions.pdf
dc.subjectAnxietyen
dc.subjectbody weighten
dc.subjectchronic stressen
dc.subjectcomfort fooden
dc.subjectcorticosteroneen
dc.subjectfood intakeen
dc.titleStress-induced endocrine response and anxiety: the effects of comfort food in ratsen
dc.typeinfo:eu-repo/semantics/article
Arquivos
Coleções
ISS - Artigos