Ocular histoplasmosis-like syndrome: a report from a nonendemic area

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dc.contributor.authorAmaro, Miguel Hage [UNIFESP]
dc.contributor.authorMuccioli, Cristina [UNIFESP]
dc.contributor.authorAbreu, Mariza Toledo [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2015-06-14T13:37:00Z
dc.date.available2015-06-14T13:37:00Z
dc.date.issued2007-08-01
dc.description.abstractPURPOSE: To report some cases of ocular histoplasmosis-like syndrome from a nonendemica area. DESIGN: Observational case series. METHODS: This is a prospective study of 16 eyes from 8 immunocompetent patients evaluated between January 2001 to September 2005. Six patients were female and 2 male aged between 20 to 44 years, average 28 years. All patients presented clinical features that resembled ocular histoplasmosis. All patients had a negative antibody test for histoplasmosis and negative medical and laboratory evaluation of toxoplasmosis, syphilis, and tuberculosis. All patients were submitted to a complete ocular examination including fluorescein angiography. One patient was submitted to indocyanine green angiography. RESULTS: Five patients presented the classical triad of clinical features that include peripapillary scarring, histo spots, choroidal neovascularization, one patient presentd enlargement of atrophic chorioretina scar, one patient presented multiple retinal pigment epithelial detachment, one, neovascularized retinal pigment epithelial detachment. Another patient presented only histo spots. CONCLUSION: These findings of ocular histoplasmosis-like syndrome in patients with negative antibody serum test from a nonendemica area suggest that other agents could cause these similar fundus findings of ocular histoplasmosis.en
dc.description.abstractOBJETIVO: Descrevemos os achados clínicos oftalmológicos de 16 olhos de 8 pacientes imunocompetentes que apresentavam características fundoscópicas da síndrome de histoplasmose ocular. MÉTODOS: Os pacientes foram submetidos aos exames oculares de rotina e ainda à fluoresceinografia e à indocianinografia, além de exames laboratoriais para histoplasmome, toxoplasmose, sífilis, síndrome de insuficiência imunológica adquirida, tuberculose. RESULTADOS: Os exames fundoscópicos, fluoresceinográficos e indocianinográficos demonstraram múltiplas coroidites em saca-bocado, atrofia peripapilar e neovascularização de coróide. Os exames laboratoriais foram considerados normais. CONCLUSÃO: Uma outra etiologia que não a histoplasmose pode ser considerada para os achados encontrados. Uma micobactéria atípica ou o Mycobacterium avium que causam lesões semelhantes às descritas nos exames oculares podem ser consideradas.pt
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Department of Ophthalmology Eye Institute
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Department of Ophthalmology Eye Institute
dc.description.affiliationUnifespUNIFESP, Department of Ophthalmology Eye Institute
dc.description.affiliationUnifespUNIFESP, Department of Ophthalmology Eye Institute
dc.description.sourceSciELO
dc.format.extent577-580
dc.identifierhttp://dx.doi.org/10.1590/S0004-27492007000400003
dc.identifier.citationArquivos Brasileiros de Oftalmologia. Conselho Brasileiro de Oftalmologia, v. 70, n. 4, p. 577-580, 2007.
dc.identifier.doi10.1590/S0004-27492007000400003
dc.identifier.fileS0004-27492007000400003.pdf
dc.identifier.issn0004-2749
dc.identifier.scieloS0004-27492007000400003
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/3805
dc.language.isoeng
dc.publisherConselho Brasileiro de Oftalmologia
dc.relation.ispartofArquivos Brasileiros de Oftalmologia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHistoplasmosisen
dc.subjectHistoplasmaen
dc.subjectEye infections, fungalen
dc.subjectChoroiditisen
dc.subjectFluorescein angiographyen
dc.subjectFundus oculien
dc.subjectChoroidal neovascularizationen
dc.subjectObservational studiesen
dc.subjectHistoplasmosept
dc.subjectHistoplasmapt
dc.subjectInfecções oculares fungicaspt
dc.subjectCoroiditept
dc.subjectAngiofluoresceinografiapt
dc.subjectFundo de olhopt
dc.subjectNeovascularização coroidalpt
dc.subjectEstudos observacionaispt
dc.titleOcular histoplasmosis-like syndrome: a report from a nonendemic areaen
dc.title.alternativeSíndrome de histoplasmose ocular símile: relato de uma área não endêmicapt
dc.typeinfo:eu-repo/semantics/article
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