Prevalence of recurrent wheezing in infants

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dc.contributor.authorChong Neto, Herberto Jose
dc.contributor.authorRosario, Nelson Augusto
dc.contributor.authorSole, Dirceu [UNIFESP]
dc.contributor.authorMallol, Javier
dc.contributor.institutionUniv Fed Parana
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniv Santiago Chile
dc.date.accessioned2016-01-24T13:48:50Z
dc.date.available2016-01-24T13:48:50Z
dc.date.issued2007-07-01
dc.description.abstractObjective: To identify the prevalence of recurrent wheezing in infants in the city of Curitiba, PR, Brazil.Methods: A cross-sectional study carried out by means of administering questionnaires to the parents of infants aged 12 to 15 months attending health centers for immunization during the period between August 2005 and December 2006. This is a standardized and validated instrument consisting of questions on demographic characteristics, wheezing, respiratory infections and risk factors. At the time of the study the City Health Department had 107 health centers, 35 of which were selected by lots and distributed homogeneously across the municipal territory.Results: A total of 1,364 infants (45.4%) had episodes of wheezing during their first 12 months of life, with onset at 5.5+/-3.1 months (mean +/- standard deviation), and 678 (22.6%) had had three or more episodes. in 84.6% of the wheezing children treatment was with beta(2)-agonists, with inhaled corticosteroids in 18.5%, oral corticosteroids in 24.3% and leukotriene receptor antagonists were used with 5.4%. the wheezing children exhibited nocturnal symptoms, intense difficulty breathing and visits to emergency services in the proportions of 58.9, 46.2 and 57.6%, respectively; 12.7% were admitted to hospital for asthma and 10.9% had had a medical diagnosis of asthma. Nocturnal symptoms, visits to emergency, severity of symptoms, hospital admissions for asthma and medical diagnoses of asthma were all more common among those who had suffered three or more crises (p < 0.001).Conclusions: There is an elevated prevalence of wheezing among the infants of Curitiba, with early onset and elevated morbidity. It is possible that these infants represent a large contingent of asthmatics.en
dc.description.affiliationUniv Fed Parana, Hosp Clin, BR-80060000 Curitiba, Parana, Brazil
dc.description.affiliationUNIFESP EPM, São Paulo, Brazil
dc.description.affiliationUniv Santiago Chile, Santiago, Chile
dc.description.affiliationUnifespUNIFESP EPM, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent357-362
dc.identifierhttp://dx.doi.org/10.2223/JPED.1679
dc.identifier.citationJornal de Pediatria. Rio de Janeiro, Rj: Soc Brasil Pediatria, v. 83, n. 4, p. 357-362, 2007.
dc.identifier.doi10.2223/JPED.1679
dc.identifier.issn0021-7557
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/29838
dc.identifier.wosWOS:000254506500012
dc.language.isoeng
dc.publisherSoc Brasil Pediatria
dc.relation.ispartofJornal de Pediatria
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titlePrevalence of recurrent wheezing in infantsen
dc.title.alternativePrevalência de sibilância recorrente em lactentespt
dc.typeinfo:eu-repo/semantics/article
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