Occupational risk factors of lung cancer in Sao Paulo, Brazil

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dc.contributor.authorWunsch, Victor
dc.contributor.authorMoncau, José Eduardo Cajado [UNIFESP]
dc.contributor.authorMirabelli, Dario
dc.contributor.authorBoffetta, Paolo
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionAgenzia Reg Protez Piemonte
dc.contributor.institutionInt Agcy Res Canc
dc.date.accessioned2018-06-18T12:11:52Z
dc.date.available2018-06-18T12:11:52Z
dc.date.issued1998-04-01
dc.description.abstractObjectives This study estimated the risk of occupational exposure for lung cancer in the metropolitan region of Sao Paulo, the largest urbanized and industrialized area in Brazil.Methods In this hospital-based case-referent study of 398 cases and 860 referents, the cases were matched to referents according to age, gender, and hospital and personally interviewed for information on lifetime job history, smoking habits, passive smoking exposure, cancer in relatives, socioeconomic status, and migratory history. The analysis concerned industrial titles and occupational categories. With the use of a job-exposure matrix, exposure to asbestos, polynuclear aromatic hydrocarbons, arsenic, dust, nickel and chromium was assessed.Results For the men in the 56 industrial and 122 occupational categories examined, an excess risk of lung cancer was found in the machinery industry [odds ratio (OR) 1.62, 95% confidence interval (95% CI) 1.02-2.55). In pottery manufacturing the risk (OR 2.21, 95% CI 1.00-4.87) was increased for workers exposed greater than or equal to 10 years (OR 6.43, 95% CI 1.12-37.01). Textile workers employed for greater than or equal to 10 years with a latency of greater than or equal to 40 years had an elevated risk (OR 21.93, 95% CI 1.96-245.0). In the analysis using the job-exposure matrix no risk was detected for the specific lung cancer carcinogens examined. For the women, no significantly elevated risk was observed.Conclusions The results of this study revealed risks of lung cancer for men in the machinery industry and for pottery and textile workers with long-term exposure.en
dc.description.affiliationUniv Sao Paulo, Fac Saude Publ, Dept Epidemiol, BR-01246904 Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Sao Paulo, Brazil
dc.description.affiliationAgenzia Reg Protez Piemonte, Grugliasco, Italy
dc.description.affiliationInt Agcy Res Canc, F-69372 Lyon, France
dc.description.affiliationUnifespUniv Fed Sao Paulo, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent118-124
dc.identifierhttp://dx.doi.org/10.5271/sjweh.288
dc.identifier.citationScandinavian Journal Of Work Environment & Health. Helsinki: Scand J Work Env Health, v. 24, n. 2, p. 118-124, 1998.
dc.identifier.doi10.5271/sjweh.288
dc.identifier.fileWOS000073656900006.pdf
dc.identifier.issn0355-3140
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/45576
dc.identifier.wosWOS:000073656900006
dc.language.isoeng
dc.publisherScand J Work Env Health
dc.relation.ispartofScandinavian Journal Of Work Environment & Health
dc.rightsAcesso aberto
dc.subjectcase-referent studyen
dc.subjectepidemiologyen
dc.subjectjob-exposure matrixen
dc.subjectlung canceren
dc.titleOccupational risk factors of lung cancer in Sao Paulo, Brazilen
dc.typeArtigo
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