OCT4 gonadal gene expression related to the presence of Y-chromosome sequences in Turner syndrome
| dc.contributor.author | Bianco, Bianca Alves Vieira [UNIFESP] | |
| dc.contributor.author | Oliveira, Kelly Cristina de [UNIFESP] | |
| dc.contributor.author | Guedes, Alexis Dourado [UNIFESP] | |
| dc.contributor.author | Barbosa, Caio Parente | |
| dc.contributor.author | Lipay, Monica Vannucci Nunes [UNIFESP] | |
| dc.contributor.author | Verreschi, Ieda Therezinha do Nascimento [UNIFESP] | |
| dc.contributor.institution | Universidade Federal de São Paulo (UNIFESP) | |
| dc.contributor.institution | ABC Sch Med | |
| dc.date.accessioned | 2016-01-24T14:05:35Z | |
| dc.date.available | 2016-01-24T14:05:35Z | |
| dc.date.issued | 2010-11-01 | |
| dc.description.abstract | To show that in the dysgenetic gonads of 104 Turner syndrome patients no significant difference was found regarding the expression of the genes DAX1, FOG2, GATA4, OCT4, SF1, SRY, TSPY, WT1, and STRA8 compared with controls, except for genes OCT4, SRY, and TSPY in both gonads of a patient whose chromosomal constitution was 45,X/45,X,add(15)(p11). the expression analysis of genes OCT4, SRY, and TSPY in the dysgenetic gonads of Turner syndrome patients may allow introducing modifications in the microenvironment that could contributed to a malignant transformation process. (Fertil Steril (R) 2010;94:2347-9. (C) 2010 by American Society for Reproductive Medicine.) | en |
| dc.description.affiliation | Universidade Federal de São Paulo, Dept Med, Div Endocrinol, São Paulo, Brazil | |
| dc.description.affiliation | ABC Sch Med, Dept Gynecol & Obstet, Div Gynecol Pathol & Human Reprod, Santo Andre, Brazil | |
| dc.description.affiliationUnifesp | Universidade Federal de São Paulo, Dept Med, Div Endocrinol, São Paulo, Brazil | |
| dc.description.source | Web of Science | |
| dc.format.extent | 2347-2349 | |
| dc.identifier | https://dx.doi.org/10.1016/j.fertnstert.2010.02.036 | |
| dc.identifier.citation | Fertility and Sterility. New York: Elsevier B.V., v. 94, n. 6, p. 2347-2349, 2010. | |
| dc.identifier.doi | 10.1016/j.fertnstert.2010.02.036 | |
| dc.identifier.issn | 0015-0282 | |
| dc.identifier.uri | https://repositorio.unifesp.br/handle/11600/33004 | |
| dc.identifier.wos | WOS:000283441400090 | |
| dc.language.iso | eng | |
| dc.publisher | Elsevier B.V. | |
| dc.relation.ispartof | Fertility and Sterility | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.rights.license | http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy | |
| dc.subject | Turner syndrome | en |
| dc.subject | Gonadal dysgenesis | en |
| dc.subject | OCT4 gene | en |
| dc.subject | SRY gene | en |
| dc.subject | TSPY gene | en |
| dc.subject | Y-chromosome | en |
| dc.title | OCT4 gonadal gene expression related to the presence of Y-chromosome sequences in Turner syndrome | en |
| dc.type | info:eu-repo/semantics/article |