Carcinoma of the vulva. Clinicopathologic factors involved in inguinal and pelvic lymph node metastasis

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dc.contributor.authorAbrao, F. S.
dc.contributor.authorBaracat, E. C.
dc.contributor.authorMarques, A. F.
dc.contributor.authorAbrao, M. S.
dc.contributor.authorTorloni, H.
dc.contributor.authorCoelho, FRG
dc.contributor.authorAlves, A. C.
dc.contributor.authorDelima, G. R.
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionLUDWIG INST CANC RES
dc.date.accessioned2018-06-15T18:11:11Z
dc.date.available2018-06-15T18:11:11Z
dc.date.issued1990-12-01
dc.description.abstractEighty-five women with vulvar squamous cell carcinoma were subjected to radical vulvectomy with bilateral inguinal and femoral node dissection or to radical vulvectomy with bilateral inguinofemoral and deep pelvic node dissection. The association between lymph node status (metastatic or not) and several parameters was analyzed: tumor location, size and clinical stage; tumor thickness, histologic grade and mitotic index; blood vessel, lymphatic and perineural infiltration; and lymphocytic and plasma cell infiltrates. There were no metastases to the pelvic lymph nodes without previous inguinal lymph node involvement. Unilateral vulvar carcinomas did not have contralateral metastatic nodes when there was no ipsilateral nodal involvement. Lymphatic vessel infiltration showed a statistically significant correlation with inguinal node metastases (P < .05). No correlation was found between lymph node metastasis and tumor size, clitoral invasion, tumor thickness, histologic grade, blood vessel and perineural infiltration, lymphocytic and plasma cell infiltrates, and mitotic index.en
dc.description.affiliationESCOLA PAULISTA MED SCH,DEPT GYNECOL,BR-04023 SAO PAULO,BRAZIL
dc.description.affiliationUNIV SAO PAULO,SCH MED,DEPT GYNECOL,SAO PAULO,BRAZIL
dc.description.affiliationLUDWIG INST CANC RES,SAO PAULO,BRAZIL
dc.description.affiliationUnifespESCOLA PAULISTA MED SCH,DEPT GYNECOL,BR-04023 SAO PAULO,BRAZIL
dc.description.sourceWeb of Science
dc.format.extent1113-1116
dc.identifier.citationJournal Of Reproductive Medicine. St Louis: Sci Printers & Publ Inc, v. 35, n. 12, p. 1113-1116, 1990.
dc.identifier.issn0024-7758
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/44631
dc.identifier.wosWOS:A1990EQ38800003
dc.language.isoeng
dc.publisherSci Printers & Publ Inc
dc.relation.ispartofJournal Of Reproductive Medicine
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.titleCarcinoma of the vulva. Clinicopathologic factors involved in inguinal and pelvic lymph node metastasisen
dc.typeinfo:eu-repo/semantics/article
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