The Use of the Esclera Scleral Contact Lens in the Treatment of Moderate to Severe Dry Eye Disease

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dc.citation.volume163
dc.contributor.authorWeber, Sarah La Porta [UNIFESP]
dc.contributor.authorde Souza, Rodrigo Becco [UNIFESP]
dc.contributor.authorPereira Gomes, Jose Alvaro [UNIFESP]
dc.contributor.authorHofling-Lima, Ana Luisa [UNIFESP]
dc.coverageNew York
dc.date.accessioned2020-08-21T17:00:12Z
dc.date.available2020-08-21T17:00:12Z
dc.date.issued2016
dc.description.abstractPURPOSE: To evaluate the efficacy of the Esclera scleral contact lens (SCL) treatment and its impact on clinical testing for moderate to severe dry eye disease (DED). DESIGN: Prospective interventional case series. METHODS: A total of 41 eyes from 25 patients with moderate to severe DED were evaluated for the Esclera SCL treatment. Best-corrected visual acuity (BCVA), tear osmolarity, the Schirmer I test, tear film breakup time (TBUT), corneal and conjunctival staining, meibo-mian grading, and Ocular Surface Disease Index and SF-36v2 questionnaires were assessed before and after the SCL treatment. These values were compared to assess the real benefit of using SCL as a treatment for DED. RESULTS: Forty-one eyes from 25 patients were fitted with SCL for management of DED. The underlying diseases were Stevens-Johnson syndrome (22 eyes), Sjogren syndrome (11 eyes), graft-vs-host disease (2 eyes), dry eye after keratomileusis in situ (2 eyes), and undifferentiated ocular surface disease (4 eyes). BCVA improved from 0.703 +/- 0.55 logMAR with habitual correction to 0.406 +/- 0.43 logMAR with SCL (P<.001). There was a significant decrease in tear osmolarity values (338.1 +/- 27.1 to 314.25 +/- 38.8 mOsm/L, P<.001) and van Bijsterveld scores (3.63 +/- 2.33 to 2.63 +/- 2.46 grade, P=.015) between the baseline and 12 months after SCL wear. There were also significant improvements in dry eye symptoms and quality of life as assessed by the OSDI and SF-36v2 questionnaires (both with P<.001). CONCLUSIONS: The Esclera SCL treatment had a positive impact on tear osmolarity and van Bijsterveld score, as well as an improvement in the patients' BCVA, dry eye symptoms, and quality of life. (C) 2016 by Elsevier Inc. All rights reserved.en
dc.description.affiliationUniv Fed Sao Paulo, Dept Ophthalmol, Ocular Surface Adv Ctr, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Ophthalmol, Ocular Surface Adv Ctr, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipBRAZILIAN GOVERNMENT COORDENACAO DE APERFEICOAMENTO DE PESSOAL DE Nivel Superior-CAPES Foundation (Brasilia, DF, Brazil)
dc.description.sponsorshipMediphacos Inc. (Belo Horizonte, MG, Brazil)
dc.format.extent167-173
dc.identifierhttp://dx.doi.org/10.1016/j.ajo.2015.11.034
dc.identifier.citationAmerican Journal Of Ophthalmology. New York, v. 163, p. 167-173, 2016.
dc.identifier.doi10.1016/j.ajo.2015.11.034
dc.identifier.fileWOS000371447500022.pdf
dc.identifier.issn0002-9394
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/57907
dc.identifier.wosWOS:000371447500022
dc.language.isoeng
dc.publisherElsevier Science Inc
dc.relation.ispartofAmerican Journal Of Ophthalmology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleThe Use of the Esclera Scleral Contact Lens in the Treatment of Moderate to Severe Dry Eye Diseaseen
dc.typeinfo:eu-repo/semantics/article
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