Risk factors for ventilator-associated pneumonia in infants and children: a cross-sectional cohort study

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dc.contributor.authorKusahara, Denise Miyuki [UNIFESP]
dc.contributor.authorEnz, Camila da Cruz [UNIFESP]
dc.contributor.authorAvelar, Ariane Ferreira Machado [UNIFESP]
dc.contributor.authorPeterlini, Maria Angélica Sorgini [UNIFESP]
dc.contributor.authorPedreira, Mavilde da Luz Gonçalves [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:38:10Z
dc.date.available2016-01-24T14:38:10Z
dc.date.issued2014-11-01
dc.description.abstractBackground the epidemiology of ventilator-associated pneumonia is well described for adults, but little information is available on risk factors for this disease in children.Objective To identify predisposing factors for ventilator-associated pneumonia in children.Methods A cross-sectional prospective cohort study of 96 patients in a 9-bed pediatric intensive care unit was performed. Variables examined were demographic characteristics, inpatient care, medications, nutrition, invasive procedures, and characteristics of mechanical ventilation. Data were analyzed by using Pearson chi(2) analysis, Fisher exact and Mann-Whitney tests, odds ratios, and forward stepwise logistic regression.Results Occurrence of ventilator-associated pneumonia correlated positively with use of nasoenteral tubes (odds ratio, 5.278; P < .001), intermittent administration of nutritional formula (odds ratio, 6.632; P = .005), emergency reintubation (odds ratio, 2.700; P = .02), use of vasoactive drugs (odds ratio, 5.108; P = .009), duration of mechanical ventilation (P < .001), and length of stay in the pediatric intensive care unit (P < .001) and in the hospital (P = .01).Conclusion Use of vasoactive drugs, presence of a nasoenteral tube, and duration of stay in the pediatric intensive care unit were independent risk factors for ventilator-associated pneumonia.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Nursing, BR-04024002 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Enfermagem, BR-04024002 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Nursing, BR-04024002 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Enfermagem, BR-04024002 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIDFAPESP: 04-13361-2
dc.format.extent469-476
dc.identifierhttps://dx.doi.org/10.4037/ajcc2014127
dc.identifier.citationAmerican Journal of Critical Care. Aliso Viejo: Amer Assoc Critical Care Nurses, v. 23, n. 6, p. 469-476, 2014.
dc.identifier.doi10.4037/ajcc2014127
dc.identifier.issn1062-3264
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/38444
dc.identifier.wosWOS:000347371300010
dc.language.isoeng
dc.publisherAmer Assoc Critical Care Nurses
dc.relation.ispartofAmerican Journal of Critical Care
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.titleRisk factors for ventilator-associated pneumonia in infants and children: a cross-sectional cohort studyen
dc.typeinfo:eu-repo/semantics/article
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