Formulas Used by Tibetan Doctors at Men-Tsee-Khang in India for the Treatment of Neuropsychiatric Disorders and Their Correlation with Pharmacological Data

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dc.contributor.authorAntonio, Raquel Luna [UNIFESP]
dc.contributor.authorKozasa, Elisa H. [UNIFESP]
dc.contributor.authorGalduroz, Jose Carlos F. [UNIFESP]
dc.contributor.authorDawa
dc.contributor.authorDorjee, Yeshi
dc.contributor.authorKalsang, Tsultrim
dc.contributor.authorNorbu, Tsering
dc.contributor.authorTenzin, Tashi
dc.contributor.authorRodrigues, Eliana [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionMen Tsee Khang Gangchen Kyishong
dc.date.accessioned2016-01-24T14:31:29Z
dc.date.available2016-01-24T14:31:29Z
dc.date.issued2013-04-01
dc.description.abstractThe aim of the present study was to identify formulas used at Men-Tsee-Khang (Tibetan Medical and Astrological Institute), India, for the treatment of neuropsychiatric disorders and to compare the Tibetan usage of particular ingredients with pharmacological data from the scientific database. Using ethnographic methods, five doctors were selected and interviewed. A correlation was observed between central nervous system disorders and rLung, one of the three humors in Tibetan medicine, which imbalance is the source of mental disorders, and ten multi-ingredient formulas used to treat the imbalance of this particular humor were identified. These formulas utilize 61 ingredients; among them were 48 plant species. Each formula treats several symptoms related to rLung imbalance, so the plants may have therapeutic uses distinct from those of the formulas in which they are included. Myristica fragrans, nutmeg, is contained in 100% of the formulas, and its seeds exhibit stimulant and depressant actions affecting the central nervous system. Preclinical and clinical data from the scientific literature indicate that all of the formulas include ingredients with neuropsychiatric action and corroborate the therapeutic use of 75.6% of the plants. These findings indicate a level of congruence between the therapeutic uses of particular plant species in Tibetan and Western medicines. Copyright (c) 2012 John Wiley & Sons, Ltd.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Psychobiol, BR-04023062 São Paulo, Brazil
dc.description.affiliationMen Tsee Khang Gangchen Kyishong, Dharmshala 176215, HP, India
dc.description.affiliationUniversidade Federal de São Paulo, Dept Biol Sci, Ctr Ethnobot & Ethnopharmacol Studies, BR-09972270 Diadema, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Psychobiol, BR-04023062 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Biol Sci, Ctr Ethnobot & Ethnopharmacol Studies, BR-09972270 Diadema, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFAP (Fundacao de Apoio a Universidade Federal de São Paulo)
dc.description.sponsorshipAFIP (Associacao Fundo de Incentivo a Pesquisa)
dc.description.sponsorshipUNIFESP International Affairs Office
dc.format.extent552-563
dc.identifierhttp://dx.doi.org/10.1002/ptr.4749
dc.identifier.citationPhytotherapy Research. Hoboken: Wiley-Blackwell, v. 27, n. 4, p. 552-563, 2013.
dc.identifier.doi10.1002/ptr.4749
dc.identifier.issn0951-418X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/36138
dc.identifier.wosWOS:000317685800011
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofPhytotherapy Research
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.subjectethnopharmacologyen
dc.subjectmedicinal plantsen
dc.subjectneuropsychiatric plantsen
dc.subjectTibetan medicineen
dc.subjecttraditional medicineen
dc.subjectMen-Tsee-Khangen
dc.titleFormulas Used by Tibetan Doctors at Men-Tsee-Khang in India for the Treatment of Neuropsychiatric Disorders and Their Correlation with Pharmacological Dataen
dc.typeinfo:eu-repo/semantics/article
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