Scintigraphy and Doppler ultrasonography for the evaluation of obstructive urinary calculi

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dc.contributor.authorGandolpho, Lilian [UNIFESP]
dc.contributor.authorSevillano, Marta Maite [UNIFESP]
dc.contributor.authorBarbieri, A. [UNIFESP]
dc.contributor.authorAjzen, Sergio Aron [UNIFESP]
dc.contributor.authorSchor, Nestor [UNIFESP]
dc.contributor.authorOrtiz, Valdemar [UNIFESP]
dc.contributor.authorHeilberg, Ita Pfeferman [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2015-06-14T13:29:25Z
dc.date.available2015-06-14T13:29:25Z
dc.date.issued2001-06-01
dc.description.abstractForty-seven patients with unilateral obstructive calculi (12 males and 35 females) were submitted to 99mTc-diethylene triamine pentaacetic acid (DTPA) or 99mTc-dimercaptosuccinic acid (DMSA) scans for assessment of renal function. The scans revealed unilateral functional deficit in 68 and 66% of the patients, respectively. A calculus size of 1.1 to 2.0 cm was significantly associated with deficit detected by DTPA, but duration of obstruction and calculus localization were not. After relief of the obstruction, the mean percent renal function of the affected kidney was found to be significantly increased from 25 ± 12% to 29 ± 12% in DTPA and from 21 ± 15% to 24 ± 12% in DMSA. Initial Doppler ultrasonography performed in 35 patients detected an increased resistive index in 10 (29%). In the remaining patients with a normal resistive index, ureteral urinary jet was observed, indicating partial obstruction. The high frequency of renal function impairment detected by DTPA and of tubulointerstitial damage detected by DMSA as well as the slight amelioration of unilateral renal function after relief of obstruction suggest that scintigraphy assessment may help evaluate the unilateral percentage of renal function and monitor renal function recovery when it occurs. The presence of a urinary jet detected by Doppler ultrasonography further indicates the severity of obstruction and the recovery prognosis.en
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Divisão de Nefrologia
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Divisão de Medicina Nuclear
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Divisão de Ultrassonografia
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Divisão de Urologia
dc.description.affiliationUnifespUNIFESP, EPM, Divisão de Nefrologia
dc.description.affiliationUnifespUNIFESP, EPM, Divisão de Medicina Nuclear
dc.description.affiliationUnifespUNIFESP, EPM, Divisão de Ultrassonografia
dc.description.affiliationUnifespUNIFESP, EPM, Divisão de Urologia
dc.description.sourceSciELO
dc.format.extent745-751
dc.identifierhttp://dx.doi.org/10.1590/S0100-879X2001000600007
dc.identifier.citationBrazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 34, n. 6, p. 745-751, 2001.
dc.identifier.doi10.1590/S0100-879X2001000600007
dc.identifier.fileS0100-879X2001000600007.pdf
dc.identifier.issn0100-879X
dc.identifier.scieloS0100-879X2001000600007
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/1176
dc.identifier.wosWOS:000169443400007
dc.language.isoeng
dc.publisherAssociação Brasileira de Divulgação Científica
dc.relation.ispartofBrazilian Journal of Medical and Biological Research
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjecturinary tract obstructionen
dc.subjectobstructive calculien
dc.subjectDTPA and DMSA scansen
dc.subjectresistive indexen
dc.subjectDoppler ultrasonographyen
dc.titleScintigraphy and Doppler ultrasonography for the evaluation of obstructive urinary calculien
dc.typeinfo:eu-repo/semantics/article
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