Role of the caudal pressor area in the regulation of sympathetic vasomotor tone
dc.contributor.author | Campos, Ruy Ribeiro [UNIFESP] | |
dc.contributor.author | Carillo, Bruno de Arruda [UNIFESP] | |
dc.contributor.author | Oliveira-Sales, Elizabeth Barbosa de [UNIFESP] | |
dc.contributor.author | Silva, Adilson Marques da [UNIFESP] | |
dc.contributor.author | Silva, Nyam Florencio da | |
dc.contributor.author | Futuro Neto, Henrique Azevedo | |
dc.contributor.author | Bergamaschi, Cassia Toledo [UNIFESP] | |
dc.contributor.institution | Universidade Federal de São Paulo (UNIFESP) | |
dc.contributor.institution | Universidade Federal do Espírito Santo Laboratório de Neuromorfologia | |
dc.contributor.institution | Universidade Federal do Espírito Santo Programa de Pós-Graduação em Ciências Fisiológicas | |
dc.contributor.institution | Santa Casa de Misericórdia de Vitória (EMESCAM) Escola Superior de Ciências | |
dc.date.accessioned | 2015-06-14T13:38:38Z | |
dc.date.available | 2015-06-14T13:38:38Z | |
dc.date.issued | 2008-07-01 | |
dc.description.abstract | It is well known that the ventrolateral medulla contains neurons involved in the tonic and reflex control of the cardiovascular system. Two regions within the ventrolateral medulla were initially identified: the rostral ventrolateral medulla (RVLM) and the caudal ventrolateral medulla (CVLM). Activation of the RVLM raises arterial blood pressure and sympathetic nerve activity, and activation of the CVLM causes opposite effects. The RVLM premotor neurons project directly to sympathetic preganglionic neurons and are involved in the maintenance of resting sympathetic vasomotor tone. A significant proportion of tonic activity in the RVLM sympathetic premotor neurons is driven by neurons located in a third region of the ventrolateral medulla denominated caudal pressor area (CPA). The CPA is a pressor region located at the extreme caudal part of the ventrolateral medulla that appears to have an important role controlling the activity of RVLM neurons. In this brief review, we will address the importance of the ventrolateral medulla neurons for the generation of resting sympathetic tone related to arterial blood pressure control focusing on two regions, the RVLM and the CPA. | en |
dc.description.affiliation | Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Disciplina de Fisiologia Cardiovascular e Respiratória | |
dc.description.affiliation | Universidade Federal do Espírito Santo Laboratório de Neuromorfologia | |
dc.description.affiliation | Universidade Federal do Espírito Santo Programa de Pós-Graduação em Ciências Fisiológicas | |
dc.description.affiliation | Santa Casa de Misericórdia de Vitória (EMESCAM) Escola Superior de Ciências | |
dc.description.affiliation | Universidade Federal de São Paulo (UNIFESP) Campus Baixada Santista Departamento de Biociênicas | |
dc.description.affiliationUnifesp | UNIFESP, EPM, Disciplina de Fisiologia Cardiovascular e Respiratória | |
dc.description.affiliationUnifesp | UNIFESP, Campus Baixada Santista Depto. de Biociênicas | |
dc.description.source | SciELO | |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | |
dc.format.extent | 557-562 | |
dc.identifier | http://dx.doi.org/10.1590/S0100-879X2008000700002 | |
dc.identifier.citation | Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 41, n. 7, p. 557-562, 2008. | |
dc.identifier.doi | 10.1590/S0100-879X2008000700002 | |
dc.identifier.file | S0100-879X2008000700002.pdf | |
dc.identifier.issn | 0100-879X | |
dc.identifier.scielo | S0100-879X2008000700002 | |
dc.identifier.uri | http://repositorio.unifesp.br/handle/11600/4465 | |
dc.identifier.wos | WOS:000259326100002 | |
dc.language.iso | eng | |
dc.publisher | Associação Brasileira de Divulgação Científica | |
dc.relation.ispartof | Brazilian Journal of Medical and Biological Research | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Rostral ventrolateral medulla | en |
dc.subject | Rat | en |
dc.subject | Glutamate | en |
dc.subject | Blood pressure | en |
dc.subject | Caudal pressor area | en |
dc.subject | Sympathetic vasomotor tone | en |
dc.title | Role of the caudal pressor area in the regulation of sympathetic vasomotor tone | en |
dc.type | info:eu-repo/semantics/article |
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