Heart Failure Survival Score in Patients With Chagas Disease: Correlation With Functional Variables

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dc.contributor.authorRitt, Luiz E. [UNIFESP]
dc.contributor.authorCarvalho, Antonio Carlos [UNIFESP]
dc.contributor.authorFeitosa, Gilson S.
dc.contributor.authorPinho-Filho, Joel A.
dc.contributor.authorMacedo, Cristiano R. B.
dc.contributor.authorVilas-Boas, Fabio
dc.contributor.authorAndrade, Marcus V. S.
dc.contributor.authorFeitosa-Filho, Gilson S.
dc.contributor.authorAlmeida, Augusto J. G.
dc.contributor.authorBarojas, Marcos
dc.contributor.authorLopes, Renato D. [UNIFESP]
dc.contributor.institutionDuke Clin Res Inst
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionHosp Santa Izabel
dc.contributor.institutionBrazilian Clin Res Inst
dc.date.accessioned2016-01-24T14:27:20Z
dc.date.available2016-01-24T14:27:20Z
dc.date.issued2012-06-01
dc.description.abstractIntroduction and objectives: Chagas disease is a prevalent cause of heart failure in Latin America, and its prognosis is worse than other etiologies. the Heart Failure Survival Score has been used to assess prognosis in patients with heart failure; however, this score has not yet been studied in patients with Chagas cardiopathy.Methods: the Heart Failure Survival Score was calculated in 55 patients with severe left ventricular systolic dysfunction due to Chagas disease. Correlations were assessed between the Heart Failure Survival Score and variables obtained from echocardiograms, cardiopulmonary exercise tests, quality-of-life measures, and 6-minute walking tests.Results: Patients were distributed among New York Heart Association classes II-IV; 89% were taking angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, 62% were taking beta-blockers, 86% were taking diuretics, and 74% were taking aldosterone receptor blockers. the mean Heart Failure Survival Score was 8.75 (0.80). the score correlated well with cardiopulmonary test variables such as peak oxygen uptake (0.662; P<.01), oxygen uptake at the anaerobic threshold (0.644; P<.01), ventilation carbon dioxide efficiency slope (-0.417; P<.01), oxygen pulse (0.375; P<.01), oxygen uptake efficiency slope (0.626; P<.01), 6-minute walking test (0.370; P<.01), left ventricle ejection fraction (0.650; P=.01), and left atrium diameter (-0.377; P<.01). There was also a borderline significant correlation between the Heart Failure Survival Score and quality of life (-0.283; P<.05).Conclusions: in heart failure patients with Chagas disease, the Heart Failure Survival Score correlated well with the main prognostic functional test variables. (c) 2011 Sociedad Espanola de Cardiologia. Published by Elsevier Espana, S.L. All rights reserved.en
dc.description.affiliationDuke Clin Res Inst, Durham, NC 27705 USA
dc.description.affiliationUniversidade Federal de São Paulo, Dept Cardiol, São Paulo, Brazil
dc.description.affiliationHosp Santa Izabel, Dept Cardiol, Salvador, BA, Brazil
dc.description.affiliationBrazilian Clin Res Inst, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Cardiol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipBrazilian Ministry of Health
dc.description.sponsorshipFoundation for Research Support of the State of Bahia
dc.description.sponsorshipBrazilian Clinical Research Institute in São Paulo, Brazil
dc.format.extent538-543
dc.identifierhttp://dx.doi.org/10.1016/j.rec.2011.12.020
dc.identifier.citationRevista Espanola de Cardiologia. Barcelona: Ediciones Doyma S A, v. 65, n. 6, p. 538-543, 2012.
dc.identifier.doi10.1016/j.rec.2011.12.020
dc.identifier.issn0300-8932
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/34961
dc.identifier.wosWOS:000305258000007
dc.language.isoeng
dc.publisherEdiciones Doyma S A
dc.relation.ispartofRevista Espanola de Cardiologia
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectCardiomyopathyen
dc.subjectHeart failureen
dc.subjectPrognosisen
dc.titleHeart Failure Survival Score in Patients With Chagas Disease: Correlation With Functional Variablesen
dc.typeinfo:eu-repo/semantics/article
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