Can hydrophilic coated catheters be beneficial for the public healthcare system in Brazil? - A cost-effectiveness analysis in patients with spinal cord injuries

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dc.citation.issue1
dc.citation.volume44
dc.contributor.authorTruzzi, Jose Carlos [UNIFESP]
dc.contributor.authorTeich, Vanessa
dc.contributor.authorPepe, Camila
dc.coverageRio De Janeiro
dc.date.accessioned2020-07-02T18:52:08Z
dc.date.available2020-07-02T18:52:08Z
dc.date.issued2018
dc.description.abstractIntroduction: Detrusor sphincter dyssynergia affects 70% to 80% of all spinal cord injury patients, resulting in increased risk of urinary tract infections (UTIs) and potential exposure to antimicrobial resistance. In Brazil, local guidelines recommend intermittent catheterization as the best method for bladder emptying, and two catheter types are available: the conventional uncoated PVC and the hydrophilic coated catheters. Objective: To evaluate the cost-effectiveness of two types of catheters for intermittent catheterization from the perspective of the Brazilian public healthcare system. Materials and Methods: A Markov model was used to evaluate cost-effectiveness in those with spinal cord injuries. A primary analysis was conducted on all possible adverse events, and a secondary analysis was performed with urinary tract infections as the only relevant parameter. The results were presented as cost per life years gained (LYG), per quality-adjusted life years (QALY) and per number of urinary tract infections (UTIs) avoided. Results: The base scenario of all adverse events shows a cost-effective result of hydrophilic coated catheters compared to uncoated PVC catheters at 57,432 BRL (Brazilian Reais) per LYG and 122,330 BRL per QALY. The secondary scenario showed that the use of hydrophilic coated catheters reduces the total number of UTIs, indicating that an additional cost of hydrophilic coated catheters of 31,240 BRL over a lifetime will reduce lifetime UTIs by 6%. Conclusions: Despite the higher unit value, the use of hydrophilic coated catheters is a cost-effective treatment from the perspective of the Brazilian public healthcare system.en
dc.description.affiliationUniv Fed Sao Paulo, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.affiliationHosp Alemao Oswaldo Cruz, Sao Paulo, SP, Brazil
dc.description.affiliationSense Co, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent121-131
dc.identifierhttp://dx.doi.org/10.1590/S1677-5538.IBJU.2017.0221
dc.identifier.citationInternational Braz J Urol. Rio De Janeiro, v. 44, n. 1, p. 121-131, 2018.
dc.identifier.doi10.1590/S1677-5538.IBJU.2017.0221
dc.identifier.fileWOS000423752200019.pdf
dc.identifier.issn1677-5538
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/53892
dc.identifier.wosWOS:000423752200019
dc.language.isoeng
dc.publisherBrazilian Soc Urol
dc.relation.ispartofInternational Braz J Urol
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCost-Benefit Analysisen
dc.subjectSpinal Cord Injuriesen
dc.subjectIntermittent Urethral Catheterizationen
dc.subjectUrinary Tract Infectionsen
dc.titleCan hydrophilic coated catheters be beneficial for the public healthcare system in Brazil? - A cost-effectiveness analysis in patients with spinal cord injuriesen
dc.typeinfo:eu-repo/semantics/article
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