Sepsis in the Postoperative Period of Cardiac Surgery: Problem Description

dc.contributor.authorOliveira, Dinaldo Cavalcanti de [UNIFESP]
dc.contributor.authorOliveira Filho, Joao Bosco de
dc.contributor.authorSilva, Rogerio Ferreira
dc.contributor.authorMoura, Simone Soares
dc.contributor.authorSilva, Diego Janstk
dc.contributor.authorEgito, Enilton Sergio Tabosa do
dc.contributor.authorMartins, Stevan Krieger
dc.contributor.authorSouza, Luis Carlos Bento
dc.contributor.authorJatene, Adib Domingos
dc.contributor.authorPiegas, Leopoldo Soares [UNIFESP]
dc.contributor.institutionUniversidade Federal de Pernambuco (UFPE)
dc.contributor.institutionHosp Coracao
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.abstractBackground: In spite of the advances in sepsis diagnosis and treatment in the last years, the morbidity and mortality are still high.Objective: To assess the prevalence, in-hospital evolution and prognosis of patients that presented sepsis in the postoperative period of cardiac surgery.Methods: This is a prospective study that included patients (n = 7,332) submitted to cardiac surgery (valvular or coronary) between January 1995 and December 2007. The classic criteria of sepsis diagnosis were used to identify the patients that developed such condition and the preoperative comorbidities, in-hospital evolution and prognosis were evaluated.Results: Sepsis occurred in 29 patients (prevalence = 0.39%). There was a predominance of the male when compared to the female sex (79% vs. 21%). Mean age was 69 +/- 6.5 years. The main preoperative comorbidities were: systemic arterial hypertension (79%), dyslipidemia (48%) and family history of coronary artery disease (38%). The mean Apache score was 18 7, whereas the Sofa score was 14.2 +/- 3.8. The primary infectious focus was pulmonary in 19 patients (55%). There were 19 positive cultures and the mean IV hydration during the first 24 hours was 1,016 +/- 803 ml. The main complications were acute renal failure (65%), low cardiac output syndrome (55%) and malignant ventricular arrhythmia (55%). Mortality was 79% (23 patients).Conclusion: The occurrence of sepsis after cardiac surgery was a rare event; however, its occurrence showed catastrophic clinical outcomes. The high morbidity and mortality showed the need to improve treatment, aiming at patients' better clinical evolution. (Arq Bras Cardiol 2010; 94(3):332-336)en
dc.description.affiliationUniv Fed Pernambuco, Hosp Clin, Recife, PE, Brazil
dc.description.affiliationHosp Coracao, Assoc Sanatorio Sirio, Recife, PE, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Hosp Sao Paulo, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Hosp Sao Paulo, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.identifier.citationArquivos Brasileiros De Cardiologia. Rio De Janeiro: Arquivos Brasileiros Cardiologia, v. 94, n. 3, p. 352-356, 2010.
dc.publisherArquivos Brasileiros Cardiologia
dc.relation.ispartofArquivos Brasileiros De Cardiologia
dc.rightsAcesso aberto
dc.subjectpostoperative careen
dc.subjectheart / surgeryen
dc.subjectthoracic surgeryen
dc.titleSepsis in the Postoperative Period of Cardiac Surgery: Problem Descriptionen
dc.title.alternativeSepse no pós-operatório de cirurgia cardíaca: descrição do problemapt