Prevalence and risk factors of metabolic syndrome in Brazilian and Italian obese adolescents: a comparison study

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dc.contributor.authorCaranti, Danielle Arisa [UNIFESP]
dc.contributor.authorLazzer, S.
dc.contributor.authorDâmaso, Ana Raimunda [UNIFESP]
dc.contributor.authorAgosti, F.
dc.contributor.authorZennaro, R.
dc.contributor.authorMello, Marco Tulio de [UNIFESP]
dc.contributor.authorTufik, Sergio [UNIFESP]
dc.contributor.authorSartorio, Alessandro
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniv Udine
dc.contributor.institutionIRCCS
dc.date.accessioned2016-01-24T13:51:46Z
dc.date.available2016-01-24T13:51:46Z
dc.date.issued2008-10-01
dc.description.abstractBackground: Metabolic syndrome (MS) prevalence between different populations in obese adolescents is scanty to date. Objective: To compare the MS prevalence and related risk factors in Brazilian and Italian obese adolescents. Methods: A total of 509 adolescents (110 Brazilian, 399 Italian), aged 15-19 years. Anthropometric characteristics, triglycerides (TG), total, low-density lipoprotein (LDL)-, high-density lipoprotein (HDL)-cholesterol, fasting plasma glucose (FPG), insulin, homeostasis model assessment of insulin resistance (HOMA-IR) and blood pressure were measured. Results: Age, body mass index (BMI) and BMI z-score were not significantly different between the two subgroups. BMI z-score, TG, FPG, HOMA-IR and systolic blood pressure (SBP) were significantly higher in boys than in girls both in Brazilian and Italian adolescents, while HDL-cholesterol levels were lower in boys than in girls. No significant differences were observed in BMI, LDL and total-cholesterol and DBP in two genders and groups. Insulin, FPG, HOMA-IR and TG were significantly higher, while LDL-cholesterol and SBP were significantly lower in Brazilian than in Italian subjects, both in males and females. HDL and total-cholesterol and diastolic blood pressure (DBP) were not significantly different between the two subgroups and genders. MS prevalence was higher in Brazilian than in Italian obese boys (34.8 vs. 23.6%, p < 0.001) and girls (15.6 vs. 12.5%, p < 0.01). the most frequently altered parameter was HOMA-IR both in subjects with MS (100% in Brazilian and 81.8% in Italian) and without MS (42.9% and 11.7%). Conclusion: Metabolic syndrome represents a worldwide emerging health problem in different ethnical populations, the alterations of the risk factors related to MS (different in their prevalence between different subgroups) being strictly linked to the degree of obesity.en
dc.description.affiliationFed Univ São Paulo UNIFESP, Postgrad Program Nutr, BR-04020060 São Paulo, Brazil
dc.description.affiliationUniv Udine, Dept Biomed Sci & Technol, I-33100 Udine, Italy
dc.description.affiliationFed Univ São Paulo UNIFESP, Dept Biosci, BR-04020060 São Paulo, Brazil
dc.description.affiliationIRCCS, Expt Lab Endocrinol Res, Italian Inst Auxol, Milan, VB, Italy
dc.description.affiliationFed Univ São Paulo UNIFESP, Dept Psychobiol, BR-04020060 São Paulo, Brazil
dc.description.affiliationIRCCS, Div Auxol, Italian Inst Auxol, Milan, VB, Italy
dc.description.affiliationUnifespFed Univ São Paulo UNIFESP, Postgrad Program Nutr, BR-04020060 São Paulo, Brazil
dc.description.affiliationUnifespFed Univ São Paulo UNIFESP, Dept Biosci, BR-04020060 São Paulo, Brazil
dc.description.affiliationUnifespFed Univ São Paulo UNIFESP, Dept Psychobiol, BR-04020060 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipAFIP
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCENESP
dc.description.sponsorshipFADA
dc.description.sponsorshipUNIFESP
dc.description.sponsorshipProgetti di Ricerca Corrente, Italian Institute for Auxology, Milan
dc.description.sponsorshipIDFAPESP/CEPID/Sleep: 9814303‐3
dc.description.sponsorshipIDFAPESP/CEPID/Sleep: 2006/00684‐3
dc.format.extent1526-1532
dc.identifierhttps://dx.doi.org/10.1111/j.1742-1241.2008.01826.x
dc.identifier.citationInternational Journal of Clinical Practice. Malden: Wiley-Blackwell, v. 62, n. 10, p. 1526-1532, 2008.
dc.identifier.doi10.1111/j.1742-1241.2008.01826.x
dc.identifier.issn1368-5031
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/30963
dc.identifier.wosWOS:000259025500012
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofInternational Journal of Clinical Practice
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.titlePrevalence and risk factors of metabolic syndrome in Brazilian and Italian obese adolescents: a comparison studyen
dc.typeinfo:eu-repo/semantics/article
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