Influence of Si substitution on the reactivity of alpha-tricalcium phosphate

dc.contributor.authorMotisuke, Mariana [UNIFESP]
dc.contributor.authorMestres, Gemma
dc.contributor.authorReno, Caroline O. [UNIFESP]
dc.contributor.authorCarrodeguas, Raul G.
dc.contributor.authorZavaglia, Cecilia A. C.
dc.contributor.authorGinebra, Maria-Pau
dc.description.abstractSilicon substituted calcium phosphates have been widely studied over the last ten years due to their enhanced osteogenic properties. Notwithstanding, the role of silicon on alpha-TCP reactivity is not clear yet. Therefore, the aim of this work was to evaluate the reactivity and the properties of Si-alpha-TCP in comparison to alpha-TCP. Precursor powders have similar properties regarding purity, particle size distribution and specific surface area, which allowed a better comparison of the Si effects on their reactivity and cements properties. Both Si-alpha-TCP and alpha-TCP hydrolyzed to a calcium-deficient hydroxyapatite when mixed with water but their conversion rates were different. Si-alpha-TCP exhibited a slower setting rate than alpha-TCP, i.e. k(SSA) for Si-TCP (0.021 g.m(-2).h(-1)) was almost four times lower than for alpha-TCP (0.072 g.m(-2).h(-1)). On the other hand, the compressive strength of the CPC resulting from fully reacted Si-alpha-TCP was significantly higher (12.80 +/- 0.38 MPa) than that of alpha-TCP (11.44 +/- 0.54 MPa), due to the smaller size of the entangled precipitated apatite crystals. (C) 2017 Published by Elsevier B.V.en
dc.description.affiliationUNIFESP, Bioceram Lab, Sci & Technol Inst, BR-12231280 Sao Jose Dos Campos, SP, Brazil
dc.description.affiliationUppsala Univ, Engn Sci Dept, Box 534, S-75121 Uppsala, Sweden
dc.description.affiliationCSIC, Dept Ceram, Inst Ceram & Glass ICV, Kelsen 5, E-28049 Madrid, Spain
dc.description.affiliationUniv Estadual Campinas, Labiomec, Mech Engn Sch, BR-13083860 Campinas, SP, Brazil
dc.description.affiliationTech Univ Catalonia, Engn Sci & Met Dept, Diagonal 647, Barcelona 08028, Spain
dc.description.affiliationUnifespUNIFESP, Bioceram Lab, Sci & Technol Inst, BR-12231280 Sao Jose Dos Campos, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipSao Paulo Research Foundation (FAPESP)
dc.description.sponsorshipSpanish Government
dc.description.sponsorshipGeneralitat de Catalunya through the ICREA Academia Award
dc.description.sponsorshipMinistry of Economy and Competitiveness of Spain
dc.description.sponsorshipIDFAPESP: 2005/04746-0
dc.description.sponsorshipIDSpanish Government: MAT2015-65601-R
dc.description.sponsorshipIDMinistry of Economy and Competitiveness of Spain: MAT2013-48426-C2-1-R
dc.identifier.citationMaterials Science & Engineering C-Materials For Biological Applications. Amsterdam, v. 75, p. 816-821, 2017.
dc.publisherElsevier Science Bv
dc.relation.ispartofMaterials Science & Engineering C-Materials For Biological Applications
dc.rightsAcesso restrito
dc.subjectalpha-Tricalcium phosphateen
dc.subjectCalcium phosphate cementen
dc.titleInfluence of Si substitution on the reactivity of alpha-tricalcium phosphateen