Gut Microbiota Differences in Children From Distinct Socioeconomic Levels Living in the Same Urban Area in Brazil

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dc.citation.issue5
dc.citation.volume63
dc.contributor.authorMello, Carolina S.
dc.contributor.authorCarmo-Rodrigues, Mirian S.
dc.contributor.authorAraujo Filho, Humberto Bezerra de [UNIFESP]
dc.contributor.authorMelli, Lígia Cristina Fonseca Lahoz [UNIFESP]
dc.contributor.authorTahan, Soraia [UNIFESP]
dc.contributor.authorPignatari, Antonio Carlos Campos [UNIFESP]
dc.contributor.authorMorais, Mauro Batista de [UNIFESP]
dc.coveragePhiladelphia
dc.date.accessioned2020-07-31T12:47:30Z
dc.date.available2020-07-31T12:47:30Z
dc.date.issued2016
dc.description.abstractObjective:To compare gut microbiota in impoverished children versus children of high socioeconomic status living in the same urban area in Brazil.Methods:A cross-sectional study was conducted to evaluate 100 children living in a slum and 30 children from a private school, ages between 5 and 11 years old, in Sao Paulo State, Brazil. To characterize the groups, data based on socioeconomic status, sanitation, and housing conditions were collected. Anthropometric measurements and neonatal data were obtained from both groups. Gut microbiota were quantified in fecal samples by real-time polymerase chain reaction.Results:The children in the private school group had higher rates of cesarean delivery and premature birth than the children in the slum group. Staphylococcus aureus (90% vs 48.0%) and Clostridium difficile (100% vs 43.0%) were more commonly found in the children from the private school than in the impoverished children (P<0.0001). C perfringens was most frequently identified in the group of children from the slum (92.0% vs 80%en
dc.description.abstractP=0.064). Higher counts of total eubacteria, Firmicutes and Bacteroidetes phyla organisms, Escherichia coli, Lactobacillus spp., and Methanobrevibacter smithii were found in the children living in poverty, whereas higher counts of Salmonella spp., C difficile, and C perfringens were observed in the children living in satisfactory housing conditions (P<0.05).Conclusions:Important differences were observed between the gut microbiota of children living under distinct socioeconomic and environmental conditions within the same city. Our findings suggest that children of high socioeconomic status have less favorable gut microbiota than do children who live in poverty.en
dc.description.affiliationUniv Fed Alagoas, Sch Nutr, Maceio, AL, Brazil
dc.description.affiliationUniv Ctr FIEO, Osasco, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Pediat, Div Pediat Gastroenterol, Rua Botucatu 598, BR-04023062 Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Med, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespDepartment of Pediatrics, Division of Pediatric Gastroenterology, Universidade Federal de São Paulo, Rua Botucatu 598, São Paulo 04023-062, SP, Brazil
dc.description.affiliationUnifespDepartment of Medicine, Universidade Federal de São Paulo, São Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent460-465
dc.identifierhttp://dx.doi.org/10.1097/MPG.0000000000001186
dc.identifier.citationJournal Of Pediatric Gastroenterology And Nutrition. Philadelphia, v. 63, n. 5, p. 460-465, 2016.
dc.identifier.doi10.1097/MPG.0000000000001186
dc.identifier.issn0277-2116
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/56866
dc.identifier.wosWOS:000386350200015
dc.language.isoeng
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofJournal Of Pediatric Gastroenterology And Nutrition
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectchilden
dc.subjectcolonen
dc.subjectenvironmental exposureen
dc.subjectmicrobiomeen
dc.titleGut Microbiota Differences in Children From Distinct Socioeconomic Levels Living in the Same Urban Area in Brazilen
dc.typeinfo:eu-repo/semantics/article
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