Sensitisation to aeroallergens in Brazilian adolescents living at the periphery of large subtropical urban centres

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dc.contributor.authorPastorino, Antonio Carlos
dc.contributor.authorKuschnir, Fabio Chigres
dc.contributor.authorArruda, Luisa Karla de Paula [UNIFESP]
dc.contributor.authorCasagrande, Rejane Rimazza Dalberto
dc.contributor.authorSouza, Renata Gontijo Lima de
dc.contributor.authorDias, Gabriela Andrade Coelho
dc.contributor.authorSilveira, H. H. N.
dc.contributor.authorCunha, Antonio Jose Ledo Alves da
dc.contributor.authorJacob, Cristina Miuki Abe [UNIFESP]
dc.contributor.authorSolé, Dirceu [UNIFESP]
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal do Rio de Janeiro (UFRJ)
dc.contributor.institutionSecretariet Civil Def
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2018-06-15T12:52:59Z
dc.date.available2018-06-15T12:52:59Z
dc.date.issued2008-01-01
dc.description.abstractObjectives: To evaluate the sensitization to aeroallergens determined by skin prick test (SPT) in Brazilian adolescents, and to correlate its positivity with the diagnosis of asthma and/or rhinitis based on the written questionnaire (WQ) of ISAAC phase III study.Patients and Methods: A total of 996 adolescents (387 boys) were selected by systematic samples. A standard allergen extracts panel (positive/negative control, D pteronyssinus [Dpt], P americana [Pal, B germanica [Bg], dog, cat, fungal and grass mix) was used and its positivity compared with positive responses to asthma, rhinitis or both.Results: Positive SPT to at least one allergen was observed in 466 adolescents (46.8 %), with sensitisation to Dpt in 79.1 %. Positivity to more than one allergen occurred in 232 students (49.8 %). The frequency of positive SPTs was significantly higher among adolescents with asthma (OR = 2.16), rhinitis (OR = 1.69), and asthma and rhinitis (OR = 2.03). Positive SPT to four or more allergens were higher among asthmatics (OR = 2.6) and among adolescents with asthma and rhinitis (OR = 3).Conclusions: A high sensitisation rate to aeroallergens was observed, significantly higher among those with asthma, rhinitis or a combination of both, especially in multiple sensitisations.en
dc.description.affiliationUniv Sao Paulo, Sch Med, Childrens Inst, Dept Paediat,Allergy & Immunol Unit, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Rio de Janeiro, Sch Med, Rio De Janeiro, Brazil
dc.description.affiliationUniv Sao Paulo, Fac Med Ribeirao Preto, Dept Internal Med, Ribeirao Preto, Brazil
dc.description.affiliationSecretariet Civil Def, Sch Hlth Program, Ribeirao Preto, Brazil
dc.description.affiliationUniv Fed Rio de Janeiro, Dept Paediat, Rio De Janeiro, Brazil
dc.description.affiliationUniv Fed Rio de Janeiro, Martagao & Gesteira Inst Child Care & Pediat, Rio De Janeiro, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Escola Paulista Med, Dept Pediat, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Escola Paulista Med, Dept Pediat, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent9-16
dc.identifierhttp://dx.doi.org/10.1157/13115665
dc.identifier.citationAllergologia Et Immunopathologia. Barcelona: Elsevier Doyma Sl, v. 36, n. 1, p. 9-16, 2008.
dc.identifier.doi10.1157/13115665
dc.identifier.issn0301-0546
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/42195
dc.identifier.wosWOS:000254251200003
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofAllergologia Et Immunopathologia
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectatopyen
dc.subjectskin prick testen
dc.subjectrisk factoren
dc.subjectasthmaen
dc.subjectrhinitisen
dc.subjectadolescenten
dc.titleSensitisation to aeroallergens in Brazilian adolescents living at the periphery of large subtropical urban centresen
dc.typeinfo:eu-repo/semantics/article
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