HIV-GB virus C co-infection: an overview

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dc.contributor.authorBaggio-Zappia, Giovana Lotici [UNIFESP]
dc.contributor.authorHernandes Granato, Celso Francisco
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionFleury Med & Hlth
dc.date.accessioned2016-01-24T13:52:10Z
dc.date.available2016-01-24T13:52:10Z
dc.date.issued2009-01-01
dc.description.abstractGB virus C (GBV-C) and hepatitis G virus (HGV) are two isolates of the same virus, independently identified in humans in the 1990s by two research laboratories, and were initially considered a potential cause of liver disease. Studies failed to associate the virus with hepatitis or any known human disease. GBV-C reappeared in the scientific scene when some research groups, in an attempt to find the interference of the virus among HIV seropositive patients, reported a lower mortality rate and slower disease progression among co-infected patients. From then on, several mechanisms have been proposed to clarify this putative benefit; however, the question whether GBV-C exerts a protective effect in HIV-infected patients remains to be resolved.en
dc.description.affiliationUniversidade Federal de São Paulo, Lab Virol & Immunol 1, Virol Lab, Infect Dis Discipline, BR-04038032 São Paulo, Brazil
dc.description.affiliationFleury Med & Hlth, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Lab Virol & Immunol 1, Virol Lab, Infect Dis Discipline, BR-04038032 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIDFAPESP: 05/576115-5
dc.description.sponsorshipIDFAPESP: 05/58901-7
dc.format.extent12-19
dc.identifierhttp://dx.doi.org/10.1515/CCLM.2009.001
dc.identifier.citationClinical Chemistry and Laboratory Medicine. Berlin: Walter de Gruyter & Co, v. 47, n. 1, p. 12-19, 2009.
dc.identifier.doi10.1515/CCLM.2009.001
dc.identifier.issn1434-6621
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/31233
dc.identifier.wosWOS:000263224200002
dc.language.isoeng
dc.publisherWalter de Gruyter & Co
dc.relation.ispartofClinical Chemistry and Laboratory Medicine
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectco-infectionen
dc.subjectGB virus Cen
dc.subjecthepatitis virusesen
dc.subjectHIVen
dc.subjectviral interferenceen
dc.titleHIV-GB virus C co-infection: an overviewen
dc.typeinfo:eu-repo/semantics/article
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