Patients with epileptic seizures and cerebral lesions who underwent lesionectomy restricted to or associated with the adjacent irritative area

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dc.contributor.authorRassi Neto, Aziz [UNIFESP]
dc.contributor.authorFerraz, Fernando Patriani [UNIFESP]
dc.contributor.authorCampos, Carlos R.
dc.contributor.authorBraga, Fernando Menezes [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T12:30:50Z
dc.date.available2016-01-24T12:30:50Z
dc.date.issued1999-07-01
dc.description.abstractPurpose: To analyze the best surgical procedure for patients with epileptic seizures and cerebral lesions-i.e., resection restricted to the lesion or resection associated with the adjacent irritative area-based on the clinical evolution of patients' seizure outcome and electroencephalographic (EEG) and electrocorticographic (ECoG) findings.Methods: This study comprised 37 patients with epileptic seizures and cerebral lesions, ranging in age from 9 to 66 years. Patients were divided into two groups: Group 1 consisted of 21 patients with medically intractable epilepsy, Group 2 of 16 patients with medically controlled epilepsy. Eleven of the 21 patients in Group 1 (Subgroup A) underwent surgical resection of the cerebral lesion and adjacent irritative area as shown by ECoG. for the remaining 10 patients in Group 1 (Subgroup B), the resection was restricted to the lesion. the 16 patients in Group 2 all underwent lesionectomies.Results: of the 11 patients in group 1 who underwent resection of the cerebral lesion and adjacent irritative area, 91% became seizure free. Sixty percent of the remaining patients in group 1 whose resections were restricted to the lesion also became seizure free, as did all the patients in group 2. An overall analysis of the EEGs for all patients showed a statistically significant decrease in paroxysmal activity.Conclusions: in patients with uncontrolled seizures, resection of the cerebral lesion associated with the irritative area shows a tendency to obtain better seizure-outcome results than restricted lesionectomy.en
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Dept Neurol & Neurosurg, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Dept Neurol & Neurosurg, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent856-864
dc.identifierhttp://dx.doi.org/10.1111/j.1528-1157.1999.tb00791.x
dc.identifier.citationEpilepsia. Philadelphia: Lippincott Williams & Wilkins, v. 40, n. 7, p. 856-864, 1999.
dc.identifier.doi10.1111/j.1528-1157.1999.tb00791.x
dc.identifier.issn0013-9580
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/26098
dc.identifier.wosWOS:000081247200006
dc.language.isoeng
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofEpilepsia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectepilepsy tumorsen
dc.subjectepilepsy surgeryen
dc.subjectlesionectomyen
dc.subjectelectrocorticographyen
dc.titlePatients with epileptic seizures and cerebral lesions who underwent lesionectomy restricted to or associated with the adjacent irritative areaen
dc.typeinfo:eu-repo/semantics/article
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