Deep anterior lamellar transplant using lyophilized and optisol corneas in patients with keratoconus

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dc.contributor.authorFarias, Roberta [UNIFESP]
dc.contributor.authorBarbosa, Luciene [UNIFESP]
dc.contributor.authorLima, Acacio
dc.contributor.authorMayumi, Eliane
dc.contributor.authorLourenco, Andrea
dc.contributor.authorFreitas, Denise de [UNIFESP]
dc.contributor.authorAllemann, Norma
dc.contributor.authorVieira, Luis
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionSorocaba Eye Bank
dc.date.accessioned2016-01-24T13:51:45Z
dc.date.available2016-01-24T13:51:45Z
dc.date.issued2008-10-01
dc.description.abstractPurpose: Prospective randomized clinical trial to evaluate the efficacy of lyophilized corneas for deep anterior lamellar keratoplasty (DALK) in patients with keratoconus.Methods: Ten eyes underwent DALK and received corneas that had been lyophilized, and 10 eyes received corneas kept in Optisol. Follow-up examinations included measurement of visual acuity (VA; Early Treatment Diabetic Retiropathy Study chart), topography, pachymetry, specular microscopy, constrast sensitivity, and confocal micorscopy.Results: All vairables improved similarly in both groups, without statistical differences between them, except for the uncorrected VA in the sixth postoperative month, which was better in the lyophilized group (0.46) compared with Optisol group (0.70). the best spectacle-corrected VA was 0.16 in the lyophilized group and 0.26 in the Optisol group. the mean endothelial cell count during the sixth postoperative month was 2778.5 in the lyophilized group and 2611.5 in the Optisol group. Optisol corneas had greater keratocyte density, and the keratocyte density improved in lyophilized corneas during follow-up.Conclusion: Lyophilized corneas can be used successfully for DALK to treat keratoconus with results similar to Optisol corneas.en
dc.description.affiliationUniversidade Federal de São Paulo, São Paulo, Brazil
dc.description.affiliationSorocaba Eye Bank, Sorocaba, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent1030-1036
dc.identifierhttp://dx.doi.org/10.1097/ICO.0b013e31817e903a
dc.identifier.citationCornea. Philadelphia: Lippincott Williams & Wilkins, v. 27, n. 9, p. 1030-1036, 2008.
dc.identifier.doi10.1097/ICO.0b013e31817e903a
dc.identifier.issn0277-3740
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/30958
dc.identifier.wosWOS:000259662600011
dc.language.isoeng
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofCornea
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectdeep anterior lamellar keratoplastyen
dc.subjectkeratoconusen
dc.subjectOptisolen
dc.subjectlyophilizationen
dc.titleDeep anterior lamellar transplant using lyophilized and optisol corneas in patients with keratoconusen
dc.typeinfo:eu-repo/semantics/article
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