Phonetic and phonological aspects of speech in Alzheimer's disease

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dc.citation.issue1
dc.citation.volume32
dc.contributor.authorCera, Maysa Luchesi
dc.contributor.authorOrtiz, Karin Zazo
dc.contributor.authorFerreira Bertolucci, Paulo Henrique
dc.contributor.authorMinett, Thais
dc.coverageAbingdon
dc.date.accessioned2020-07-02T18:52:02Z
dc.date.available2020-07-02T18:52:02Z
dc.date.issued2018
dc.description.abstractBackground: Alzheimer's disease (AD) can involve changes in communication and can lead to mutism in severe cases. Oral communication may be impaired by phonetic-motor disorders, such as apraxia of speech (AOS), or by language disorders, such as aphasia. Therefore, the identification of manifestations of AOS and phonemic paraphasias in patients with AD is critical to understanding the communication changes and determining the therapeutic planning. Aims: To identify the distribution of phonetic-phonological manifestations in older patients with AD and healthy older subjects and assess whether these manifestations indicate the origin of the changes, including a predominantly phonetic-motor origin, a predominantly phonological-linguistic origin, or both. Methods & Procedures: This cross-sectional study evaluated 90 patients with AD and 30 healthy older volunteers. All of the participants underwent the same repetition task for phonetic and phonological assessments using the current classification of phonetic-phonological manifestationsen
dc.description.abstractthis classification distinguishes characteristics that are mostly related to AOS from other signs that are mostly related to aphasia. Negative binomial regression analysis was conducted to compare the amount of each manifestation presented by the two groups. Outcomes & Results: The patients with AD showed significantly more signs of aphasia (self-correction, and vowel and consonant substitutions), AOS (prolonged intervals and extended vowel duration), and AOS or aphasia (distortion, omission, attempts at the syllable level, distorted substitutions, and additions) than the healthy older volunteers. Conclusions: Older adults with AD presented phonetic and phonological changes of aphasia and AOS and, consequently, limitations in symbolic-linguistic planning and motor planning.en
dc.description.affiliationUniv Brasilia, Ceilandia Campus, Brasilia, DF, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Speech Language & Hearing Sci, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Neurol & Neurosurg, Sao Paulo, Brazil
dc.description.affiliationUniv Cambridge, Dept Radiol, Cambridge, England
dc.description.affiliationUniv Cambridge, Inst Publ Hlth, Cambridge, England
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Speech Language & Hearing Sci, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Neurol & Neurosurg, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipState of Sao Paulo Research Foundation (FAPESP) [2008/52670-1]
dc.description.sponsorshipNational Council for Scientific and Technological Development (CNPq) [132979/2008-0]
dc.description.sponsorshipCoordination for the Improvement of Higher Education Personnel (CAPES)
dc.description.sponsorshipAcademic Clinical Fellow from the National Institute for Health Research
dc.description.sponsorshipIDFAPESP [2008/52670-1]
dc.description.sponsorshipIDCNPq [132979/2008-0]
dc.format.extent88-102
dc.identifierhttp://dx.doi.org/10.1080/02687038.2017.1362687
dc.identifier.citationAphasiology. Abingdon, v. 32, n. 1, p. 88-102, 2018.
dc.identifier.doi10.1080/02687038.2017.1362687
dc.identifier.issn0268-7038
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/53835
dc.identifier.wosWOS:000427198800006
dc.language.isoeng
dc.publisherRoutledge Journals, Taylor & Francis Ltd
dc.relation.ispartofAphasiology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectSpeech-language pathologyen
dc.subjectAlzheimer's diseaseen
dc.subjectspeechen
dc.subjectlanguageen
dc.subjectagingen
dc.titlePhonetic and phonological aspects of speech in Alzheimer's diseaseen
dc.typeinfo:eu-repo/semantics/article
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