Sentinel lymph node biopsy in cutaneous melanoma
dc.contributor.author | Oliveira, Andrea Fernandes de [UNIFESP] | |
dc.contributor.author | Santos, Ivan Dunshee de Abranches Oliveira [UNIFESP] | |
dc.contributor.author | Tucunduva, Thaís Cardoso de Mello [UNIFESP] | |
dc.contributor.author | Sanches, Luciana Garbelini [UNIFESP] | |
dc.contributor.author | Oliveira Filho, Renato Santos de [UNIFESP] | |
dc.contributor.author | Enokihara, Mílvia Maria Simões e Silva [UNIFESP] | |
dc.contributor.author | Ferreira, Lydia Masako [UNIFESP] | |
dc.contributor.institution | Universidade Federal de São Paulo (UNIFESP) | |
dc.date.accessioned | 2015-06-14T13:37:09Z | |
dc.date.available | 2015-06-14T13:37:09Z | |
dc.date.issued | 2007-10-01 | |
dc.description.abstract | PURPOSE: To assess the importance of sentinel lymph node biopsy in patients with cutaneous melanoma. METHODS: Ninety consecutive non-randomized patients with stages I and II melanoma who underwent sentinel lymph node biopsy were followed up prospectively for six years. RESULTS: Patients were followed up for a mean period of 30 months. Their mean age was 53.3 years, ranging from 12 to 83 years. Thirty patients were male (37.5%) and 50, female (62.5%). Sentinel lymph node was positive in 32.5% and negative in 67.5%. It was found that the thicker the tumor, the greater the incidence of positive sentinel lymph nodes. In the group of patients with positive sentinel lymph nodes, recurrence occurred in 43.5%, but in those with negative sentinel lymph nodes, in only 7%, what points out to the association of tumor recurrence and positive sentinel lymph nodes. There were no major postoperative complications. CONCLUSION: Sentinel lymph node biopsy was demonstrated to be a safe method for selecting patients who need therapeutic lymphadenectomy. | en |
dc.description.abstract | OBJETIVO: Avaliar a importância da biópsia do linfonodo sentinela em pacientes com melanoma cutâneo MÉTODOS: Noventa pacientes com estadiamento I e II foram acompanhados prospectivamente no período de seis anos, de forma consecutiva e não randomizada e submetidos a biópsia do linfonodo sentinela. RESULTADOS: Os pacientes foram acompanhados durante tempo médio de 30 meses. A média de idade dos pacientes foi de 53,3 anos, variando de 12 a 83. Quanto ao sexo, foram avaliados 30 pacientes do sexo masculino (37,5%) e 50 do sexo feminino (62,5%).32,5% dos pacientes apresentaram linfonodo sentinela positivo e 67,5% linfonodo sentinela negativos. Comparando-se a espessura tumoral com a positividade do LS, verificou-se que quanto maior a espessura, maior a incidência de positividade do linfonodo sentinela. No grupo de pacientes com LS positivo a recorrência surgiu em 43,5% dos casos, mostrando a relação entre a recorrência e a positividade do LS. Não houve complicações no pós-operatório. CONCLUSÃO: A biópsia do linfonodo sentinela mostrou-se um método seguro para selecionar os pacientes que necessitam de linfadenectomia terapêutica. | pt |
dc.description.affiliation | UNIFESP Post-Graduation Program in Plastic Surgery | |
dc.description.affiliation | UNIFESP Surgery Department Head of Plastic Surgery Division | |
dc.description.affiliation | UNIFESP | |
dc.description.affiliation | UNIFESP Surgery Department Plastic Surgery Division | |
dc.description.affiliation | UNIFESP Physician of Pathology Department | |
dc.description.affiliation | UNIFESP Surgery Department | |
dc.description.affiliationUnifesp | UNIFESP, Post-Graduation Program in Plastic Surgery | |
dc.description.affiliationUnifesp | UNIFESP, Surgery Department Head of Plastic Surgery Division | |
dc.description.affiliationUnifesp | UNIFESP, Surgery Department Plastic Surgery Division | |
dc.description.affiliationUnifesp | UNIFESP, Physician of Pathology Department | |
dc.description.affiliationUnifesp | UNIFESP, Surgery Department | |
dc.description.source | SciELO | |
dc.format.extent | 332-336 | |
dc.identifier | http://dx.doi.org/10.1590/S0102-86502007000500002 | |
dc.identifier.citation | Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 22, n. 5, p. 332-336, 2007. | |
dc.identifier.doi | 10.1590/S0102-86502007000500002 | |
dc.identifier.file | S0102-86502007000500002.pdf | |
dc.identifier.issn | 0102-8650 | |
dc.identifier.scielo | S0102-86502007000500002 | |
dc.identifier.uri | http://repositorio.unifesp.br/handle/11600/3964 | |
dc.identifier.wos | WOS:000258573400003 | |
dc.language.iso | eng | |
dc.publisher | Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia | |
dc.relation.ispartof | Acta Cirurgica Brasileira | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Melanoma | en |
dc.subject | Lymph Nodes | en |
dc.subject | Lymphatic Vessels | en |
dc.subject | Diagnosis | en |
dc.subject | Melanoma | pt |
dc.subject | Linfonodos | pt |
dc.subject | Vasos Linfáticos | pt |
dc.subject | Diagnóstico | pt |
dc.title | Sentinel lymph node biopsy in cutaneous melanoma | en |
dc.title.alternative | Biópsia do linfonodo sentinela no melanoma cutâneo | pt |
dc.type | info:eu-repo/semantics/article |
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