Impact of a program to prevent central line-associated bloodstream infection in the zero tolerance era

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dc.contributor.authorMarra, Alexandre R.
dc.contributor.authorRodrigues Cal, Ruy Guilherme
dc.contributor.authorDurao, Marcelino Souza [UNIFESP]
dc.contributor.authorCorrea, Luci
dc.contributor.authorGuastelli, Luciana Reis
dc.contributor.authorMoura, Denis Faria
dc.contributor.authorEdmond, Michael B.
dc.contributor.authorPavao dos Santos, Oscar Fernando [UNIFESP]
dc.contributor.institutionHosp Israelita Albert Einstein
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionVirginia Commonwealth Univ
dc.date.accessioned2016-01-24T14:05:16Z
dc.date.available2016-01-24T14:05:16Z
dc.date.issued2010-08-01
dc.description.abstractBackground: Central line-associated bloodstream infection (CLABSI) is one of the most important health care-associated infections in the critical care setting.Methods: A quasiexperimental study involving multiple interventions to reduce the incidence of CLABSI was conducted in a medical-surgical intensive care unit (ICU) and in 2 step-down units (SDUs). From March 2005 to March 2007 (phase 1 [P1]), some Centers for Disease Control and Prevention evidence-based practices were implemented. From April 2007 to April 2009 (P2), we intervened in these processes at the same time that performance monitoring was occurring at the bedside, and we implemented the Institute for Healthcare Improvement central line bundle for all ICU and SDU patients requiring central venous lines.Results: the mean incidence density of CLABSI per 1000 catheter-days in the ICU was 6.4 in phase 1 and 3.2 in phase 2, P < .001. the mean incidence density of CLABSI per 1000 catheter-days in the SDUs was 4.1 in phase 1 and 1.6 in phase 2, P = 5.005.Conclusion: These results suggest that reducing CLABSI rates in an ICU setting is a complex process that involves multiple performance measures and interventions that can also be applied to SDU settings.en
dc.description.affiliationHosp Israelita Albert Einstein, Intens Care Unit, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Div Nephrol, EPM, São Paulo, Brazil
dc.description.affiliationHosp Israelita Albert Einstein, Infect Control Unit, São Paulo, Brazil
dc.description.affiliationVirginia Commonwealth Univ, Sch Med, Dept Internal Med, Richmond, VA USA
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Div Nephrol, EPM, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent434-439
dc.identifierhttp://dx.doi.org/10.1016/j.ajic.2009.11.012
dc.identifier.citationAmerican Journal of Infection Control. New York: Mosby-Elsevier, v. 38, n. 6, p. 434-439, 2010.
dc.identifier.doi10.1016/j.ajic.2009.11.012
dc.identifier.issn0196-6553
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/32775
dc.identifier.wosWOS:000280231600004
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofAmerican Journal of Infection Control
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectBloodstream infectionen
dc.subjectpreventionen
dc.subjectintensive care uniten
dc.subjectstep-down uniten
dc.subjectzero toleranceen
dc.subjectcentral venous catheteren
dc.subjectepidemiologyen
dc.subjectcentral line bundleen
dc.titleImpact of a program to prevent central line-associated bloodstream infection in the zero tolerance eraen
dc.typeinfo:eu-repo/semantics/article
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