RETINAL NEOVASCULARIZATION SECONDARY TO PROLIFERATIVE DIABETIC RETINOPATHY CHARACTERIZED BY SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY

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dc.contributor.authorCho, Hyung
dc.contributor.authorAlwassia, Ahmad A.
dc.contributor.authorRegiatieri, Caio V. [UNIFESP]
dc.contributor.authorZhang, Jason Y.
dc.contributor.authorBaumal, Caroline
dc.contributor.authorWaheed, Nadia
dc.contributor.authorDuker, Jay S.
dc.contributor.institutionTufts Med Ctr
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:31:21Z
dc.date.available2016-01-24T14:31:21Z
dc.date.issued2013-03-01
dc.description.abstractPurpose: the purpose of this study was to characterize diabetic retinal neovascularization (NV) and accompanying retinal and vitreal morphologic changes using high-resolution spectral domain optical coherence tomography.Methods: A cross-sectional retrospective analysis was performed on 16 eyes of 14 nonconsecutive subjects with proliferative diabetic retinopathy that were seen between August 2011 and December 2011 at the New England Eye Center, Boston, MA. Patients who had NV of the disk, NV elsewhere, and intraretinal microvascular abnormalities were scanned using optical coherence tomography directly over the region of the abnormal vessels.Results: Characteristic changes of the retinal vasculature, retina, and vitreous were seen in the 16 eyes with NV. This study describes optical coherence tomography characteristics of 1) NV of the disk, 2) NV elsewhere, 3) intraretinal microvascular abnormality, 4) NV causing traction without retinal detachment; and 5) NV causing traction with retinal detachment. the morphologic appearance of vitreous traction was found to be consistent with the previous histologic reports.Conclusion: It is possible to image diabetic NV using spectral domain optical coherence tomography and to visualize the spectrum of retinal, retinal vascular, and vitreal changes seen through these areas of abnormal retinal vasculature. RETINA 33:542-547, 2013en
dc.description.affiliationTufts Med Ctr, New England Eye Ctr, Dept Ophthalmol, Boston, MA 02111 USA
dc.description.affiliationUniversidade Federal de São Paulo, Dept Ophthalmol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Ophthalmol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipResearch to Prevent Blindness
dc.description.sponsorshipNIH
dc.description.sponsorshipAir Force Office of Scientific Research
dc.description.sponsorshipMassachusetts Lions Eye Research Fund
dc.description.sponsorshipCarl Zeiss Meditech, Inc
dc.description.sponsorshipOptovue, Inc
dc.description.sponsorshipTopcon Medical Systems, Inc
dc.description.sponsorshipIDNIH: RO1-EY11289-23
dc.description.sponsorshipIDNIH: R01-EY13178-07
dc.description.sponsorshipIDNIH: R01-EY013516-07
dc.description.sponsorshipIDAir Force Office of Scientific Research: FA9550-07-1-0101
dc.description.sponsorshipIDAir Force Office of Scientific Research: FA9550-07-1-0014
dc.format.extent542-547
dc.identifierhttp://dx.doi.org/10.1097/IAE.0b013e3182753b6f
dc.identifier.citationRetina-the Journal of Retinal and Vitreous Diseases. Philadelphia: Lippincott Williams & Wilkins, v. 33, n. 3, p. 542-547, 2013.
dc.identifier.doi10.1097/IAE.0b013e3182753b6f
dc.identifier.issn0275-004X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/36051
dc.identifier.wosWOS:000315455200011
dc.language.isoeng
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofRetina-the Journal of Retinal and Vitreous Diseases
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectneovascularization of the retinaen
dc.subjectneovascularization of the disken
dc.subjectintraretinal microvascular abnormalitiesen
dc.subjectdiabetes mellitusen
dc.subjectproliferative diabetic retinopathyen
dc.subjectoptical coherence tomographyen
dc.titleRETINAL NEOVASCULARIZATION SECONDARY TO PROLIFERATIVE DIABETIC RETINOPATHY CHARACTERIZED BY SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHYen
dc.typeinfo:eu-repo/semantics/article
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