Inappropriate prescribing of compounded antiobesity formulas in Brazil

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dc.contributor.authorNappo, S. A.
dc.contributor.authorDe Oliveira, E. M.
dc.contributor.authorMorosini, S.
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade Federal de Pernambuco (UFPE)
dc.date.accessioned2016-01-24T12:30:34Z
dc.date.available2016-01-24T12:30:34Z
dc.date.issued1998-05-01
dc.description.abstractVolunteers posing as patients underwent paid medical consultations at the offices of 107 Brazilian doctors (in two Brazilian cities) with the purpose of obtaining an antiobesity prescription. in 80.3% of 71 São Paulo visits, as well as in 47.2% of 36 Recife visits, compounded preparations were prescribed. Four to six active components predominated, but there were prescriptions listing as many as 17 components. All contained anorectic substances and benzodiazepines. Diuretics, thyroid agents, laxatives, medicinal plants, and a variety of other substances were often included. the prescribed doses were frequently above recommended limits, reaching amounts as much as live times the internationally defined standard doses. in some instances two anorectic substances were prescribed simultaneously. Most doctors failed to warn volunteers of the possible occurrence of adverse reactions to the prescribed substances. Furthermore, in the case of all volunteers involved, antiobesity prescriptions would be completely unnecessary, a fact that points to improper medical conduct on the part of doctors. It is concluded that the practice by some Brazilian medical doctors of prescribing manipulation formulas based on anorectic and benzodiazepine drugs is a greater hazard than a benefit to patients. (C) 1998 John Wiley & Sons, Ltd.en
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Dept Psicobiol, BR-04023062 São Paulo, Brazil
dc.description.affiliationUniv Fed Pernambuco, Recife, PE, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Dept Psicobiol, BR-04023062 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent207-212
dc.identifierhttp://dx.doi.org/10.1002/(SICI)1099-1557(199805/06)7:3<207
dc.identifier.citationPharmacoepidemiology and Drug Safety. W Sussex: John Wiley & Sons Ltd, v. 7, n. 3, p. 207-212, 1998.
dc.identifier.doi10.1002/(SICI)1099-1557(199805/06)7:3<207
dc.identifier.issn1053-8569
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/25890
dc.identifier.wosWOS:000074814800007
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofPharmacoepidemiology and Drug Safety
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.subjectmedical prescriptionen
dc.subjectantiobesity drugsen
dc.subjectanorectic drugsen
dc.subjectdiethylpropionen
dc.subjectfenproporexen
dc.subjectmagistral formulasen
dc.subjectd,1-fenfluramineen
dc.subjectd-fenfluramine weight-reducing drugsen
dc.titleInappropriate prescribing of compounded antiobesity formulas in Brazilen
dc.typeinfo:eu-repo/semantics/article
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