Southwick's angle determination during growth hormone treatment and its usefulness to evaluate risk of epiphysiolysis

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dc.contributor.authorAndrade, Anenisia Coelho de
dc.contributor.authorLongui, Carlos Alberto
dc.contributor.authorDamasceno, Francisco L. V.
dc.contributor.authorSantili, Claudio
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionSanta Casa São Paulo Fac Med Sci
dc.date.accessioned2016-01-24T13:52:07Z
dc.date.available2016-01-24T13:52:07Z
dc.date.issued2009-01-01
dc.description.abstractGrowth hormone (GH) replacement seems to represent an additional risk factor for epiphysiolysis. the femoral diaphyseal-epiphyseal angle (Southwick's angle), which is observed to become decreased in the presence of slipped capital femoral epiphysis, is increased in risk groups, such as obese patients, suggesting a potential marker for epiphysiolysis. To evaluate the pattern of Southwick's angle in GH deficiency (GHD) patients, we measured it in 44 GHD patients. We found that Southwick's angle increased significantly after 2 years on GH replacement compared with the pretreatment period. Our data suggest that increasing in Southwick's angle during GH treatment might represent an increased risk for epiphysiolysis in GHD patients. J Pediatr Orthop B 18:11-15 (C) 2009 Wolters Kluwer Health / Lippincott Williams & Wilkins.en
dc.description.affiliationSanta Casa São Paulo Fac Med Sci, Pediat Endocrinol Unit, Dept Pediat, São Paulo, Brazil
dc.description.affiliationSanta Casa São Paulo Fac Med Sci, Pediat Orthoped Grp, Orthoped & Traumatol Dept, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCAPE'S scholarship program
dc.format.extent11-15
dc.identifierhttp://dx.doi.org/10.1097/BPB.0b013e328318c6f3
dc.identifier.citationJournal of Pediatric Orthopaedics-part B. Philadelphia: Lippincott Williams & Wilkins, v. 18, n. 1, p. 11-15, 2009.
dc.identifier.doi10.1097/BPB.0b013e328318c6f3
dc.identifier.issn1060-152X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/31201
dc.identifier.wosWOS:000262057700003
dc.language.isoeng
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofJournal of Pediatric Orthopaedics-part B
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectepiphysiolysisen
dc.subjectgrowth hormone deficiencyen
dc.subjectslipped capital femoral epiphysisen
dc.subjectSouthwick's angleen
dc.titleSouthwick's angle determination during growth hormone treatment and its usefulness to evaluate risk of epiphysiolysisen
dc.typeinfo:eu-repo/semantics/article
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