Use of respiratory medication in five Latin American cities: the PLATINO study

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dc.contributor.authorOca, Maria Montes de
dc.contributor.authorTalamo, Carlos
dc.contributor.authorPerez-Padilla, Rogelio
dc.contributor.authorLopez, Maria Victorina
dc.contributor.authorMuino, Adriana
dc.contributor.authorJardim, Jose Roberto B. [UNIFESP]
dc.contributor.authorValdivia, Gonzalo
dc.contributor.authorPertuze, Julio
dc.contributor.authorMoreno, Dolores
dc.contributor.authorHalbert, Ronald J.
dc.contributor.authorMenezes, Ana Maria B.
dc.contributor.authorPLATINO Team
dc.contributor.institutionCent Univ Venezuela
dc.contributor.institutionInst Resp Dis
dc.contributor.institutionUniv Republica
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionPontificia Univ Catolica Chile
dc.contributor.institutionUniv Calif Los Angeles
dc.contributor.institutionUniv Fed Pelotas
dc.date.accessioned2016-01-24T13:51:45Z
dc.date.available2016-01-24T13:51:45Z
dc.date.issued2008-10-01
dc.description.abstractBackground: There is scanty information regarding respiratory medication prescription pattern in Latin America. We examined the use of bronchodilators and corticosteroids in a population-based study conducted in five Latin American cities.Methods: Medication use was derived from questions regarding the use of medication to help breathing within the previous 12 months, type of medicine, and frequency of use. To minimize the possibility of overdiagnosis, we used postbronchodilator FEV(1)/FVC < 0.70 plus FEV(1)< 80% as the definition of obstruction.Results: Interviews were completed in 5571 subjects from 6711 eligible individuals, and spirometry was performed in 5314 subjects. There were 360 (6.5%) treated subjects and 5211 not treated. Treated subjects were more likely to be older, women, unemployed, have higher tobacco consumption, higher body mass index, higher FEV, reversibility and airway obstruction. They were also more likely to report prior spirometry, prior diagnosis of COPD, asthma or tuberculosis, and more respiratory symptoms. Over half of treated subjects had neither obstruction nor FEV, reversibility, and approximately 30% reported no prior diagnosis of asthma or COPD. Prior respiratory diagnoses and wheezing were more strongly associated with treatment than objective measures of airway obstruction.Conclusions: the use of bronchodilators and/or corticosteroids is common in the general population aged 40 years or older, with over one-half of treated subjects using them without being obstructed. (c) 2008 Elsevier B.V. All rights reserved.en
dc.description.affiliationCent Univ Venezuela, Fac Med, Hosp Univ Caracas, Serv Neumonol, Caracas, Venezuela
dc.description.affiliationInst Resp Dis, Mexico City 14080, DF, Mexico
dc.description.affiliationUniv Republica, Fac Med, Hosp Maciel, Montevideo, Uruguay
dc.description.affiliationUniversidade Federal de São Paulo, BR-04021070 São Paulo, Brazil
dc.description.affiliationPontificia Univ Catolica Chile, Fac Med, Dept Salud Publ, Santiago, Chile
dc.description.affiliationPontificia Univ Catolica Chile, Fac Med, Catedra Neumol, Santiago, Chile
dc.description.affiliationUniv Calif Los Angeles, Sch Publ Hlth, Los Angeles, CA 90066 USA
dc.description.affiliationUniv Fed Pelotas, Fac Med, BR-96030002 Pelotas, RS, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, BR-04021070 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipAsociacion Latinoamericana de Torax (ALAT)
dc.description.sponsorshipBoehringer Ingelheim GmbH
dc.format.extent788-793
dc.identifierhttp://dx.doi.org/10.1016/j.pupt.2008.06.003
dc.identifier.citationPulmonary Pharmacology & Therapeutics. London: Academic Press Ltd Elsevier B.V., v. 21, n. 5, p. 788-793, 2008.
dc.identifier.doi10.1016/j.pupt.2008.06.003
dc.identifier.issn1094-5539
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/30950
dc.identifier.wosWOS:000262944200012
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofPulmonary Pharmacology & Therapeutics
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectBronchodilatorsen
dc.subjectChronic obstructive pulmonary diseaseen
dc.subjectEpidemiologyen
dc.subjectPrevalenceen
dc.subjectSteroidsen
dc.titleUse of respiratory medication in five Latin American cities: the PLATINO studyen
dc.typeinfo:eu-repo/semantics/article
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