Etiology-specific outcomes of intracytoplasmic sperm injection in azoospermic patients

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dc.contributor.authorPasqualotto, Fábio F.
dc.contributor.authorRossi, Lia Mara
dc.contributor.authorGuilherme, Patricia
dc.contributor.authorOrtiz, Valdemar [UNIFESP]
dc.contributor.authorIaconelli, Assumpto
dc.contributor.authorBorges Junior, Edson
dc.contributor.institutionFertil Ctr Assisted Reprod
dc.contributor.institutionJundiai Med Sch
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T12:37:41Z
dc.date.available2016-01-24T12:37:41Z
dc.date.issued2005-03-01
dc.description.abstractObjective: To assess fertilization, pregnancy, and miscarriage rates after intracytoplasmic sperm injection (ICSI) with epididymal or testicular spermatozoa from different types of azoospermia.Design: Retrospective study.Setting: Academic medical center and private fertility center.Patient(s): Two hundred twelve patients underwent 257 ICSI cycles.Intervention(s): Cycles of ICSI were divided into four groups according to the etiology of azoospermia: A (nonobstruction), B (postvasectomy), C (congenital obstruction), and D (obstruction due to infection). Testicular sperm aspiration and percutaneous epididymal sperm aspiration were the sperm retrieval methods used for ICSI.Main Outcome Measure(s): Fertilization, pregnancy, and miscarriage rates.Result(s): Normal fertilization rates were higher in groups C (67.7%) and B (64.1%) compared with groups A (47.3%) and D (58.9%). Although lower pregnancy rates were seen in group A, no statistical differences were detected among groups. However, the miscarriage rate was higher in group A (45.6%) compared with groups B (25.25%), C (24%), and D (22.58%).Conclusion(s): Although no differences were detected in the pregnancy rates across groups, fertilization and implantation rates were higher in patients with congenital obstruction of the seminal path. the pregnancy rate was higher and the miscarriage rate lower when epididymal sperm was used compared with testicular sperm. (c) 2005 by American Society for Reproductive Medicine.en
dc.description.affiliationFertil Ctr Assisted Reprod, BR-01401002 São Paulo, Brazil
dc.description.affiliationJundiai Med Sch, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Urol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Urol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent606-611
dc.identifierhttp://dx.doi.org/10.1016/j.fertnstert.2004.08.033
dc.identifier.citationFertility and Sterility. New York: Elsevier B.V., v. 83, n. 3, p. 606-611, 2005.
dc.identifier.doi10.1016/j.fernstert.2004.08.033
dc.identifier.issn0015-0282
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/28159
dc.identifier.wosWOS:000227637600015
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofFertility and Sterility
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectazoospermiaen
dc.subjectICSIen
dc.subjectcongenitalen
dc.subjectspermatozoaen
dc.subjecttesticleen
dc.subjectepididymisen
dc.titleEtiology-specific outcomes of intracytoplasmic sperm injection in azoospermic patientsen
dc.typeinfo:eu-repo/semantics/article
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