Herpes zoster ophthalmicus and varicella zoster virus vasculopathy

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dc.citation.issue2
dc.citation.volume79
dc.contributor.authorBandeira, Francisco[UNIFESP]
dc.contributor.authorRoizenblatt, Marina[UNIFESP]
dc.contributor.authorLevi, Guido Carlos[UNIFESP]
dc.contributor.authorde Freitas, Denise[UNIFESP]
dc.contributor.authorBelfort, Rubens, Jr.[UNIFESP]
dc.coverageSao Paulo
dc.date.accessioned2020-08-21T16:59:59Z
dc.date.available2020-08-21T16:59:59Z
dc.date.issued2016
dc.description.abstractHerpes zoster (HZ) corresponds to the reactivation of varicella zoster virus (VZV). Among adults, the ophthalmic division of the trigeminal nerve is one of the most common sites of involvement. Vasculopathy caused by HZ is associated with significant morbidity and mortality, affecting structures such as the brain, which can lead to stroke. In this review, we analyzed the epidemiological and clinical aspects of the vascular involvement of VZV, focusing on the peculiarities of its association with ocular HZ. A review of the available literature indicated that ocular involvement of HZ was a risk factor for vasculopathy after adjusting for age, sex, body mass index, smoking, indicators of metabolic syndrome, and vascular and heart diseases. Considering the severity of this complication, vascular disease mediated by VZV requires early diagnosis and aggressive treatment. Finally, the anti-HZ vaccine has been recommended as a prophylactic measure in the elderly, but it should be used with caution in immunocompromised individuals.en
dc.description.affiliationUniv Fed Sao Paulo UNIFESP, EPM, Dept Ophthalmol & Visual Sci, Sao Paulo, SP, Brazil
dc.description.affiliationSoc Brasileira Imunizacao, Sao Paulo, SP, Brazil
dc.description.affiliationInst Visao, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo UNIFESP, EPM, Dept Ophthalmol & Visual Sci, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent126-129
dc.identifierhttp://dx.doi.org/10.5935/0004-2749.20160038
dc.identifier.citationArquivos Brasileiros De Oftalmologia. Sao Paulo, v. 79, n. 2, p. 126-129, 2016.
dc.identifier.doi10.5935/0004-2749.20160038
dc.identifier.fileS0004-27492016000200126-en.pdf
dc.identifier.issn0004-2749
dc.identifier.scieloS0004-27492016000200126
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/57822
dc.identifier.wosWOS:000377714700018
dc.language.isoeng
dc.publisherConsel Brasil Oftalmologia
dc.relation.ispartofArquivos Brasileiros De Oftalmologia
dc.rightsAcesso aberto
dc.subjectHerpesvirus 3en
dc.subjecthumanen
dc.subjectHerpes zoster ophthalmicusen
dc.subjectStrokeen
dc.subjectHerpes zoster vaccineen
dc.titleHerpes zoster ophthalmicus and varicella zoster virus vasculopathyen
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