Microsurgical tracheotomy: A pediatric model in growing rats

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dc.contributor.authorManna, MCB
dc.contributor.authorMontero, EFD
dc.contributor.authorLeao, JQD
dc.contributor.authorNovo, N. F.
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T12:33:39Z
dc.date.available2016-01-24T12:33:39Z
dc.date.issued2003-01-01
dc.description.abstractPrevious studies described controversial opinions about pediatric tracheotomy concerning type of tracheal incision and long-term results, which remain as important research subjects. Experimental studies on rat tracheas are scarce, probably because of technical difficulties related to the structures' small dimensions. As many rat organ and system operative procedures were studied successfully by using microsurgical techniques, we decided to develop a pediatric tracheotomy model in growing rats which would permit long-term studies. Forty-four Wistar EPM-1 growing rats weighing 86 g and aged 35 days were divided into three groups: submitted to longitudinal, transverse, and segment excision of the trachea. Under sterile technique and intramuscular anesthesia (ketamine/xylazine), the trachea was exposed and incised, according to group, and a hand-made endotracheal cannula was inserted into the organ. This cannula was assembled using a segment of 1.5-cm-long 3 French silicone catheter passed through hexagonal-shaped silicone screen. the tracheal cannula was removed after 7 days, when we evaluated body weight, secretions, and dehiscence. in conclusion, this microsurgical tracheotomy model in growing rats is feasible, allowing studies on long-term repercussions of pediatric tracheotomy. (C) 2003 Wiley-Liss, Inc.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Surg, Escola Paulista Med, Div Operat Tech & Expt Surg, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Dept Epidemiol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Surg, Escola Paulista Med, Div Operat Tech & Expt Surg, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Dept Epidemiol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent530-534
dc.identifierhttp://dx.doi.org/10.1002/micr.10161
dc.identifier.citationMicrosurgery. New York: Wiley-liss, v. 23, n. 5, p. 530-534, 2003.
dc.identifier.doi10.1002/micr.10161
dc.identifier.issn0738-1085
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/27085
dc.identifier.wosWOS:000186223500027
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofMicrosurgery
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.titleMicrosurgical tracheotomy: A pediatric model in growing ratsen
dc.typeinfo:eu-repo/semantics/article
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