Pituitary Apoplexy After a Single Dose of Long-Acting Octreotide

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dc.contributor.authorChang, Claudia Veiga
dc.contributor.authorFelicio, Andre Carvalho [UNIFESP]
dc.contributor.authorNunes, Vania dos Santos
dc.contributor.authorCarneiro da Cunha-Neto, Malebranche Berardo
dc.contributor.authorBarros de Castro, Ana Valeria
dc.contributor.institutionUniv Estadual Paulista
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T13:59:08Z
dc.date.available2016-01-24T13:59:08Z
dc.date.issued2010-01-01
dc.description.abstractPituitary apoplexy (PA) is a rare and potentially life-threatening syndrome resulting from an acute infarction or hemorrhage of the pituitary gland. Although the pathogenesis is not fully understood, some predisposing factors such as pituitary stimulation tests, diabetes mellitus, anticoagulant or antiplatelet aggregation therapy, head trauma, and high blood pressure may play a role in its pathophysiology. Octreotide is the mainstay of medical treatment for acromegaly. the majority of reported complications of octreotide therapy are gastrointestinal. We report the case of a 51-year-old acromegalic woman who developed pituitary apoplexy within the context of high blood pressure and a single dose of long-acting octreotide. Our data suggest that the combination of hypertension and octreotide therapy enhances the risk of pituitary apoplexy.en
dc.description.affiliationUniv Estadual Paulista, Dept Endocrinol, São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Neuroendocrinol Div, Neurosurg Unit, BR-09500900 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Neurol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Neurol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent15-16
dc.identifierhttp://dx.doi.org/10.1097/TEN.0b013e3181cb47fc
dc.identifier.citationEndocrinologist. Philadelphia: Lippincott Williams & Wilkins, v. 20, n. 1, p. 15-16, 2010.
dc.identifier.doi10.1097/TEN.0b013e3181cb47fc
dc.identifier.issn1051-2144
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/32134
dc.identifier.wosWOS:000274057900006
dc.language.isoeng
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofEndocrinologist
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectacromegalyen
dc.subjectpituitary apoplexyen
dc.subjectoctreotideen
dc.subjecthypertensionen
dc.titlePituitary Apoplexy After a Single Dose of Long-Acting Octreotideen
dc.typeinfo:eu-repo/semantics/article
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