Standard full-field electroretinography in healthy preterm infants

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dc.contributor.authorBerezovsky, Adriana [UNIFESP]
dc.contributor.authorMoraes, NSB
dc.contributor.authorNusinowitz, S.
dc.contributor.authorSalomão, Solange Rios [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionJules Stein Eye Inst
dc.date.accessioned2016-01-24T12:34:07Z
dc.date.available2016-01-24T12:34:07Z
dc.date.issued2003-11-01
dc.description.abstractThe purpose of this study was to determine electroretinographic parameters according to the standard protocol from the International Society for Clinical Electrophysiology of Vision (ISCEV) in healthy preterm infants with normal fundus. Seventeen healthy preterm infants with normal fundus were recruited and divided in two age groups: 3-week group, nine infants with mean adjusted age at test = 2.67 +/- 0.92 weeks and 8-week group, eight infants with mean adjusted age at test = 7.92 +/- 1.72 weeks. Full-field ERGs were obtained with a Burian-Allen bipolar contact lens electrode from the anesthetized cornea in one eye, through a fully dilated pupil after 30 min of dark adaptation. the standard ISCEV protocol was used and the following responses were recorded: rod, maximal, oscillatory potentials, cone and 30 Hz flicker. Median values and 1st, 5th, 95th and 99th percentiles for amplitude and implicit time are described for both age groups. There was statistically larger amplitude for 30 Hz flicker (t = 2.191; p = 0.046) and for cone response (t = 2.307; p = 0.044) in the 8-week-old group. Statistically shorter implicit times were found in 8-week group for rod response (t = 3.219; p = 0.015), cone response (t = 2.839; p = 0.016) and flicker response (t = 3.326; p = 0.005). Shortening of implicit time was evident in the older group of preterms and this finding is consistent with other maturational studies confirming the anatomical and functional development of the photoreceptors. Medians and ranges between the 1st and 99th and the 5th and 95th percentiles can be used as a baseline for future comparisons with infants with ROP.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Ophthalmol, BR-04023062 São Paulo, Brazil
dc.description.affiliationJules Stein Eye Inst, Los Angeles, CA 90024 USA
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Ophthalmol, BR-04023062 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent243-249
dc.identifierhttp://dx.doi.org/10.1023/B:DOOP.0000005333.76622.c2
dc.identifier.citationDocumenta Ophthalmologica. Dordrecht: Kluwer Academic Publ, v. 107, n. 3, p. 243-249, 2003.
dc.identifier.doi10.1023/B:DOOP.0000005333.76622.c2
dc.identifier.issn0012-4486
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/27472
dc.identifier.wosWOS:000187637700005
dc.language.isoeng
dc.publisherKluwer Academic Publ
dc.relation.ispartofDocumenta Ophthalmologica
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectelectroretinographyen
dc.subjectinfantsen
dc.subjectprematurityen
dc.subjectretinal developmenten
dc.subjectvisionen
dc.titleStandard full-field electroretinography in healthy preterm infantsen
dc.typeinfo:eu-repo/semantics/article
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