Application of corneal tomography before keratorefractive procedure for laser vision correction

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dc.citation.issue5
dc.citation.volume9
dc.contributor.authorLuz, Allan [UNIFESP]
dc.contributor.authorLopes, Bernardo [UNIFESP]
dc.contributor.authorSalomao, Marcela
dc.contributor.authorAmbrosio, Renato [UNIFESP]
dc.coverageWeinheim
dc.date.accessioned2020-07-22T13:22:56Z
dc.date.available2020-07-22T13:22:56Z
dc.date.issued2016
dc.description.abstractEctasia after refractive surgery represents a major concern among refractive surgeons. Corneal abnormalities and preexisting corneal ectasia are the most important risk factors. Corneal topography and central corneal thickness are the factors traditionally screening for in refractive surgery candidates. Study of the anterior surface by Placido topography allows for identification of keratoconus before biomicroscopy. However, this is insufficient for the evaluation of pre-operative refractive surgery. There are cases of ectasia after laser in situ keratomilusis (LASIK) without identifiable risk factors such that there is a need to go beyond the corneal surface. A key requirement is quantifying susceptibility to corneal biomechanical instability and progression to ectasia. Tomographic indices derived from elevation maps and pachymetry spatial variation produce a Belin Ambrosio display final D index (BAD-D index), which has shown better results compared to surface curvature indices for detecting very mild forms of ectasia. A logistic regression formula, integrating age, residual stromal bed, and BAD-D (Ectasia Susceptibility Score, ESS) resulted in a significant improvement in accuracy, leading to 100% sensitivity and 94% specificity for detecting susceptible cases. A comprehensive corneal structural analysis based on corneal segmental tomography can detect susceptible corneas, which increases safety for refractive surgery patients. [GRAPHICS] .en
dc.description.affiliationUniv Fed Sao Paulo, Dept Ophthalmol, Sao Paulo, Brazil
dc.description.affiliationHosp Olhos Sergipe, Cornea & Refract Surg Dept, Aracaju, Brazil
dc.description.affiliationRio de Janeiro Corneal Tomog & Biomech Study Grp, Rio De Janeiro, Brazil
dc.description.affiliationInst Olhos Renato Ambrosio & Visare Personal Lase, Rio De Janeiro, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Ophthalmol, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent445-453
dc.identifierhttp://dx.doi.org/10.1002/jbio.201500236
dc.identifier.citationJournal Of Biophotonics. Weinheim, v. 9, n. 5, p. 445-453, 2016.
dc.identifier.doi10.1002/jbio.201500236
dc.identifier.issn1864-063X
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/55956
dc.identifier.wosWOS:000376070800003
dc.language.isoeng
dc.publisherWiley-V C H Verlag Gmbh
dc.relation.ispartofJournal Of Biophotonics
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectrefractive surgeryen
dc.subjectkeratoconusen
dc.subjectcorneal tomographyen
dc.subjectcorneal ectasiaen
dc.subjectLASIKen
dc.titleApplication of corneal tomography before keratorefractive procedure for laser vision correctionen
dc.typeinfo:eu-repo/semantics/article
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