Photorefractive Keratectomy With Mitomycin C After Penetrating and Lamellar Keratoplasty

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dc.contributor.authorForseto, Adriana dos Santos
dc.contributor.authorMarques, Junia Cabral
dc.contributor.authorNose, Walton [UNIFESP]
dc.contributor.institutionEye Clin Day Hosp
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:05:32Z
dc.date.available2016-01-24T14:05:32Z
dc.date.issued2010-10-01
dc.description.abstractPurpose: To assess the safety and efficacy of photorefractive keratectomy with mitomycin C (PRK-MMC) to correct refractive errors after corneal transplantation.Methods: This was a prospective and noncomparative study of 36 eyes that underwent PRK-MMC after penetrating (n = 34) or lamellar (n = 2) keratoplasty. After mechanical epithelial removal and photoablation, a sponge with mitomycin C 0.02% was applied to the stromal bed for 1 minute. the uncorrected and best-corrected visual acuities, refraction, and complications were assessed.Results: the average follow-up was 16.27 +/- 8.38 months (range, 6-30.5 months). the spherical equivalent decreased from -3.95 +/- 4.11 to -1.07 +/- 1.45 diopters (D) postoperatively (P < 0.001). the mean preoperative astigmatism was 4.42 +/- 1.69 D (range, 1.00-7.25 D); however, surgical correction was limited to 6.00 D. Vector analysis of astigmatic correction showed an index of success of 55%. At the last follow-up, 41.7% (n = 15) and 61.1% (n = 22) of the eyes were within +/- 0.50 and +/- 1.00 D of emmetropia, respectively. Nineteen eyes (52.8%) achieved an uncorrected visual acuity of 20/40 or better. the best-corrected visual acuity remained within 1 line of the preoperative values in 26 cases (72.2%), improved in 8 (22.2%), and decreased in 2 (5.6%). Endothelial cell decompensation was observed in 1 eye (2.8%) 11 months postoperatively, and haze developed in 3 cases (8.3%).Conclusions: PRK-MMC may be an option to correct refractive errors after keratoplasty. A low preoperative endothelial cell count and haze may affect the safety outcomes.en
dc.description.affiliationEye Clin Day Hosp, BR-04502001 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Paulista Sch Med, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Paulista Sch Med, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent1103-1108
dc.identifierhttp://dx.doi.org/10.1097/ICO.0b013e3181d0fecd
dc.identifier.citationCornea. Philadelphia: Lippincott Williams & Wilkins, v. 29, n. 10, p. 1103-1108, 2010.
dc.identifier.doi10.1097/ICO.0b013e3181d0fecd
dc.identifier.issn0277-3740
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/32968
dc.identifier.wosWOS:000282133100005
dc.language.isoeng
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofCornea
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectastigmatismen
dc.subjectkeratoplastyen
dc.subjectmyopiaen
dc.subjectphotorefractive keratectomyen
dc.subjectrefractive surgeryen
dc.titlePhotorefractive Keratectomy With Mitomycin C After Penetrating and Lamellar Keratoplastyen
dc.typeinfo:eu-repo/semantics/article
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